3-[(2-Bromo-4-ethylphenoxy)methyl]piperidine+hydrochloride
Catalog Number:
(34172-138)
Supplier:
MilliporeSigma
Description:
For use in the Van Gieson connective tissue stain and Mallory's aniline blue connective tissue stain
Catalog Number:
(10348-354)
Supplier:
Bioss
Description:
Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.
Catalog Number:
(10781-914)
Supplier:
Biosensis
Description:
Neurofilaments can be defined as the intermediate or 10nm diameter filaments found in neuronal cells. They are composed a mixture of subunits which often includes the neurofilament triplet proteins, NF-L, NF-M and NF-H. Neurofilaments may also include peripherin, alpha-internexin, nestin and in some cases vimentin. Alpha-internexin is a ~66 kDa Class IV intermediate filament subunit expressed in large amounts early in neuronal development, but is downregulated in many neurons as development procedes. Many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M and NF-H. In some mature neurons alpha-internexin is the only neurofilament subunit expressed. Antibodies to alpha-internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. In addition the very early developmental expression of alpha-internexin means its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage.
Catalog Number:
(10099-800)
Supplier:
Prosci
Description:
Organelles of the secretory and endocytic pathways are distinguished by their luminal acidity, which is generated by the activity of an electrogenic vacuolar-type hydrogen ATPase. Progressive acidification of vesicles in the endocytic pathway is essential for the redistribution and degradation of internalized membrane proteins, such as ligand receptor complexes and fluid-phase solutes. It may play an important role in maintaining cation homeostasis and function of the trans-Golgi network.Organelles of the secretory and endocytic pathways are distinguished by their luminal acidity, which is generated by the activity of an electrogenic vacuolar-type hydrogen ATPase. Progressive acidification of vesicles in the endocytic pathway is essential for the redistribution and degradation of internalized membrane proteins, such as ligand receptor complexes and fluid-phase solutes. This gene is expressed predominantly in the trans-Golgi network, and mediates the influx of sodium or potassium in exchange for hydrogen. It may thus play an important role in maintaining cation homeostasis and function of the trans-Golgi network. This gene is part of a gene cluster on chromosome Xp11.23.Organelles of the secretory and endocytic pathways are distinguished by their luminal acidity, which is generated by the activity of an electrogenic vacuolar-type hydrogen ATPase. Progressive acidification of vesicles in the endocytic pathway is essential for the redistribution and degradation of internalized membrane proteins, such as ligand receptor complexes and fluid-phase solutes. This gene is expressed predominantly in the trans-Golgi network, and mediates the influx of sodium or potassium in exchange for hydrogen. It may thus play an important role in maintaining cation homeostasis and function of the trans-Golgi network. This gene is part of a gene cluster on chromosome Xp11.23.
Catalog Number:
(10307-572)
Supplier:
Bioss
Description:
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Catalog Number:
(103331-534)
Supplier:
Novus Biologicals
Description:
The NDUFB6 Antibody from Novus Biologicals is a mouse polyclonal antibody to NDUFB6. This antibody reacts with human. The NDUFB6 Antibody has been validated for the following applications: Western Blot.
Catalog Number:
(10281-104)
Supplier:
Bioss
Description:
Eukaryotic gene transcription is regulated by sequence-specific transcription factors that bind modular cis acting promoter and enhancer elements. The ATF/CREB transcription factor family binds the palindromic cAMP response element (CRE) octanucleotide TGACGTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB3 and Luman), CREM-1, CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. This family of proteins contain highly divergent N-terminal domains, but share a C-terminal leucine zipper for dimerization and DNA binding. ATF-5 (ATFx), which can localize to the cytoplasm or the nucleus, binds DNA as a dimer. It interacts with CCND3 and PTP4A1.
Supplier:
Enzo Life Sciences
Description:
Fatty acid synthase inhibitor
Supplier:
AMBEED, INC
Description:
Benzylbis(triphenylphosphine)palladium(II) chloride 98%
Catalog Number:
(103331-514)
Supplier:
Novus Biologicals
Description:
The NDUFA8 Antibody from Novus Biologicals is a mouse polyclonal antibody to NDUFA8. This antibody reacts with human. The NDUFA8 Antibody has been validated for the following applications: Western Blot.
Supplier:
Bachem Americas
Description:
For additional calpain inhibitors, please see also our L-trans-Epoxysuccinyl Peptides.
Supplier:
Enzo Life Sciences
Description:
HPV type 16/18/31/33/51 probe can be optimized for use with polymer detection system or as optimized RTU with Enzo's streptavidin detection methods.
Supplier:
BeanTown Chemical
Description:
CAS: 548-62-9; EC No: 208-953-6; MDL No: MFCD00011750; RTECS: BO9000000
UN No: UN3077; Haz Class: 9; Packing Group: III
Powder; Molecular Formula: C25H30ClN3; MW: 407.99
Melting Point: 205° (decomposes)
Catalog Number:
(10303-846)
Supplier:
Bioss
Description:
The eight members of the recently identified Suppressor of Cytokines Signaling (SOCS) family are SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS6, SOCS7, and CIS. Structurally the SOCS proteins are composed of an N- terminal region of variable length and amino acid composition, a central SH2 domain, and a C-terminal motif called the SOCS box. The SOCS proteins appear to form part of a classical negative feedback loop that regulates cytokine signal transduction. Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways. During Th1 differentiation a reduction in the association of Jak1 with the IL4 Receptor correlated with the appearance of SOCS5. SOCS5 protein was preferentially expressed in committed Th1 cells and interacted with the cytoplasmic region of the IL4 Receptor alpha chain irrespective of receptor tyrosine phosphorylation. This unconventional interaction of SOCS5 protein with IL4 Receptor resulted in the inhibition of IL4-mediated signal transducer and activator of transcription-6 activation. T cells from transgenic mice constitutively expressing SOCS5 exhibited a significant reduction of IL4-mediated Th2 development. Therefore, the induced SOCS5 protein in Th1 differentiation environment may play an important role by regulating Th1 and Th2 balance.
Catalog Number:
(103331-566)
Supplier:
Novus Biologicals
Description:
The NDUFS5 Antibody from Novus Biologicals is a rabbit polyclonal antibody to NDUFS5. This antibody reacts with human. The NDUFS5 Antibody has been validated for the following applications: Western Blot.
Catalog Number:
(101411-032)
Supplier:
Electron Microscopy Sciences
Description:
Brown and Brenn Method reagent for Gram Positive and Gram Negative Bacteria
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