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(6-(Methoxycarbonyl)naphthalen-2-yl)boronic+acid
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(6-(Methoxycarbonyl)naphthalen-2-yl)boronic+acid
Supplier:
VWR International
Description:
Ideal for general-purpose applications.
Supplier:
VWR International
Description:
These general-purpose vials are available in either a short form or capsule style.
Supplier:
VWR International
Description:
This rugged, wide mouth, autoclavable PP bottle holds full vacuum for up to 24 hours.
Supplier:
TCI America
Description:
CAS Number: 23364-44-5
MDL Number: MFCD00074959 Molecular Formula: C14H15NO Molecular Weight: 213.28 Purity/Analysis Method: >99.0% (GC,T) Form: Crystal Melting point (°C): 144 Specific rotation [a]20/D: 7 deg (C=0.6, EtOH)
Catalog Number:
(IC15058980)
Supplier:
MP Biomedicals
Description:
Cesium chloride is used for the preparation of electrically conducting glasses. It is also used to make solutions for the separation of RNA from DNA by density gradient centrifugation.
Supplier:
VWR International
Description:
Long life tubing for pharma and bioprocess applications.
Supplier:
Adipogen
Description:
Vorinostat (SAHA, MK0683, Zolinza) inhibits the enzymatic activity of histone deacetylases HDAC1, HDAC2 and HDAC3 (Class I) and HDAC6 (Class II) at nanomolar concentrations (IC50<lt/> 86 nM). These enzymes catalyze the removal of acetyl groups from the lysine residues of histones proteins. In some cancer cells, there is an overexpression of HDACs, or an aberrant recruitment of HDACs to oncogenic transcription factors causing hypoacetylation of core nucleosomal histones. By inhibiting histone deacetylase, vorinostat causes the accumulation of acetylated histones and induces cell cycle arrest and/or apoptosis of some transformed cells. The mechanism of the antineoplastic effect of vorinostat has not been fully characterized.
Supplier:
Adipogen
Description:
Afatinib is an irreversible kinase inhibitor and binds to the kinase domains of EGFR (ErbB1), HER2 (ErbB2), and HER4 (ErbB4) to inhibit tyrosine kinase autophosphorylation. This results in a downregulation of ErbB signaling and subsequent inhibition of proliferation of cell lines expressing wild-type EGFR, selected EGFR exon 19 deletion mutations, or exon 21 L858R mutations. It also inhibited in vitro proliferation of cell lines overexpressing HER2. Overall, tumor growth was inhibited by Afatinib very effectively with low nanomolar IC(50) values ranging from approximately 6nM to below 500nM.
Supplier:
Adipogen
Description:
Precursor of cholesterol and vitamin D3. It is reduced to cholesterol by the enzyme 3beta-hydroxysterol-Delta7-reductase (DHCR7) in the last step of cholesterol biosynthesis. Mutations in the gene encoding DHCR7 lead to increased levels of 7-DHC and the neurodevelopmental syndrome Smith-Lemli-Opitz syndrome (SLOS). 7-DHC is used as a biomarker for SLOS screenings. Inhibits human fibroblast sphingomyelinase. Shown to have cytotoxic effects on melanoma cells. In skin, photolysis of 7-DHC by ultraviolet light produces vitamin D3. UV/Vis: lambdamax 271, 282, 293nm.
Catalog Number:
(IC15376525)
Supplier:
VWR International
Description:
Natural rubber stoppers feature a hollow plug to fit inside bottles, flasks, vials, or tubing.
Supplier:
VWR International
Description:
This rugged slide storage cabinet is manufactured from 24 gauge steel with a baked epoxy finish to ensure that slides can be stored with confidence.
Catalog Number:
(80058-450)
Supplier:
MilliporeSigma
Description:
An antioxidant and a selective lipoxygenase (LOX) inhibitor (IC50=200nM, 30µM and 30µM for 5-LOX, 12-LOX and 15-LOX, respectively) over cyclooxygenase (IC50=100µM)
Supplier:
VWR International
Description:
Excellent choice for viscous fluids.
Catalog Number:
(101411-010)
Supplier:
Electron Microscopy Sciences
Description:
Alcoholic stain solutions are available with Congo Red 0.2%, Hematoxylin 1% in 95% alcohol, Iodine 0.5% in 95% alcohol, Iodine 0.5% in 85% alcohol, Iodine 2% in 85% alcohol, Saffron 6%, Thionin 0.5% in 20% alcohol, Aldehyde Fuchsin and Alum Hematoxylin.
Supplier:
MP Biomedicals
Description:
Folic acid, also known as folate, is a B vitamin that can be found in a variety of fruits and vegetables. It can also be chemically synthesized. Folate, a watersoluble vitamin, helps the body form red blood cells and aids in the formation of genetic material within every body cell. This product exhibits metal binding properties. Hematopoietic vitamin present, free or combined with one or more additional molecules of L-(+)-glutamic acid, in liver, kidney, mushrooms, spinach, yeast, green leaves, and grasses.
Folic acid (Vitamin B9 and folate) is essential to numerous bodily functions. The human body needs folate to synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions. It is especially important in aiding rapid cell division and growth, such as in infancy and pregnancy. Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon’ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics). Very slightly soluble in cold water (0.0016 mg/mL at 25 °C), soluble to about 1% in boiling water. Slightly soluble in methanol, appreciably less soluble in ethanol and butanol. Insoluble in acetone, chloroform, ether, benzene. Relatively soluble in acetic acid, phenol, pyridine, solutions of alkali hydroxides and carbonates. Soluble in hot dilute HCl and H2SO4.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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