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4-Propoxy[1,1'-biphenyl]-3-carbaldehyde
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4-Propoxy[1,1'-biphenyl]-3-carbaldehyde
Supplier:
Adipogen
Description:
JNJ-7706621 is a dual inhibitor of cyclin-dependent kinases (CDK) and aurora kinases. It demonstrates highest potency on CDK1/2 with IC(50) values of 9nM and 4nM respectively. It shows more than 6-fold selectivity for CDK1/2 over CDK3/4/6.
Supplier:
Adipogen
Description:
Fluorescent dye. Fluorophore standard that is widely used in enzyme assay systems. Precursor for a variety of R110-based enzyme substrates for flow cytometric measurements. Used as a calibration standard for R110-based enzyme substrates. Compared to AMC and AFC enzyme substrates, fluorogenic R110 substrates are generally more sensitive, giving longer absorption and fluorescence wavelength than AMC and AFC substrates. Spectral data: lambdaex 498nm| lambdaem 520nm in methanol.
Supplier:
MP Biomedicals
Description:
Vincristine Sulfate, a dimeric Vinca alkaloid. Experiments have reported Vincristine Sulfate to demonstrate a capacity to suppress growth of proliferating cells through marked apoptosis. The cell death caused by this agent seems to result in a sustained accumulation of endogenous ceramide levels. Ceramide, has been proposed as a lipid second messenger with specific antiproliferative mediating responses.
Supplier:
Thermo Scientific Chemicals
Description:
Solubilizes proteins by reducing disulfide linkages
Catalog Number:
(IC19136105)
Supplier:
MP Biomedicals
Description:
An antiseptic and disinfectant agent. It is effective against a wide range of bacteria, some fungi and some viruses, and an agent for the prevention of gingivitis. Commercial ophthalmic products have used this agent to replace thimerosal as a preservative; however, it can cause skin irritation.
Supplier:
MP Biomedicals
Description:
Bromocresol Purple is used as a pH indicator (5.2-6.8 : yellow to blue-purple). Used in spectrophotometric determination of serum-albumin.
Catalog Number:
(102988-356)
Supplier:
Adipogen
Description:
Antidiabetic agent. Potent and selective partial agonist of peroxisome proliferator-activated receptor gamma (PPARgamma), a nuclear receptor regulating lipid and glucose metabolism. Has nanomolar binding affinity to PPARgamma and micromolar binding to the isotypes PPARalpha and PPARbeta/delta. Glucose-lowering agent. Improves insulin sensitivity, glucose tolerance and blood lipid variables without increase of fat storage or hepatoxicity. Shows potent PPARgamma-dependent anti-inflammatory activity. Potent NF-kappaB activation inhibitor by the suppression of IkappaBalpha degradation, p65 nuclear translocation and DNA-binding activity. Antimicrobial agent.
Catalog Number:
(102538-588)
Supplier:
Matrix Scientific
Description:
MF=C7H15NO MW=129.20 CAS=1484-84-0 MDL=MFCD00005989 100G
Supplier:
Adipogen
Description:
Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells. Extracellular Abeta40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer's Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly interfering with subcellular compartmentalization and lipid rafts properties, shifting gamma-secretase activity toward Abeta42 generation. Induces a reversible mitochondrial phenotype reminiscent of the one observed in AD brains. Tool to detect inhibitors of Aftin-induced actions (potential anti-AD compounds).
Supplier:
Thermo Scientific Chemicals
Description:
Petroleum refining, as acid catalyst, nucleating agent for titanium dioxide pigment, manufacturing of rubbers and lubricants
Catalog Number:
(BJ34726-500ML)
Supplier:
Honeywell Research Chemicals
Description:
Coulometric Karl Fischer titrations normally require two reagent solutions: an anolyte (the solution in the anodic compartment) and a catholyte (the solution in the cathodic compartment).
Supplier:
MP Biomedicals
Description:
Soluble in water (50 mg/l- clear, colorless to slight yellowish solution) or methanol; less soluble in ethanol; practically insoluble in ether and ethyl acetate.
Catalog Number:
(102988-362)
Supplier:
Adipogen
Description:
Antidiabetic agent. Potent and selective partial agonist of peroxisome proliferator-activated receptor gamma (PPARgamma), a nuclear receptor regulating lipid and glucose metabolism. Has low nanomolar binding affinity to PPARgamma and micromolar binding to the isotypes PPARalpha and PPARbeta/delta. The binding affinity constant to PPARgamma is 12 times lower than Amorfrutin A . Glucose-lowering agent. Improves insulin sensitivity, glucose tolerance and blood lipid variables without increase of fat storage or hepatoxicity. Shows potent PPARgamma-dependent anti-inflammatory activity. Antimicrobial agent.
Supplier:
MP Biomedicals
Description:
Azure B Certified is used for differentiating cellular RNA (purplish) and DNA (blue-green) in plant tissues. Useful as a stain for Negri Bodies. Can be used in the Romanowsky-type stains for blood and blood protozoa.
Catalog Number:
(80058-660)
Supplier:
MilliporeSigma
Description:
A non-steroidal anti-inflammatory drug that interferes with TNF-induced NF-[kappa]B activation by inhibiting phosphorylation and subsequent degradation of the I[kappa]B-[alpha] protein. Selectively inhibits TNF-induced activation of p42 (ERK2) and p44 (ERK1) MAP kinases. Also inhibits TNF-induced activation of JNK. Induces apoptosis via p38 kinase activation. Inhibits COX-2 and inducible NOS (iNOS) transcription independently of NF-[kappa]B activation.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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