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4-(Pyridin-2-yldisulfanyl)butanoic+acid
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4-(Pyridin-2-yldisulfanyl)butanoic+acid
Supplier:
Adipogen
Description:
Bentamapimod (AS602801) is a novel and orally active c-Jun-N-Terminal Kinase Inhibitor highly specific for JNK kinases. The inhibitor Bentamapimod (AS602801) is a potent anti-inflammatory agent which has been shown to reduce the disease burden in several pre-clinical models for endometriosis, and has the potential to be effective in addressing the causes of post-operative abdominal adhesions. Pre-clinical data have demonstrated Bentamapimod to be an effective anti-inflammatory compound with anti-fibrotic properties. Bentamapimod (AS602801) showed good bioavailability in rats (F=50%). It does cross the blood brain barrier, with 98% brain penetration the drug has been well tolerated so far. Bentamapimod (AS602801) is a potent and selective JNK inhibitor with therapeutic potential in MS and fibrosis as well.
Catalog Number:
(103011-384)
Supplier:
Anaspec Inc
Description:
The benzothiazole dye thioflavin T (ThT) is a classic amyloid stain for senile plaques containing bA4 peptide in Alzheimer's disease brain.
Catalog Number:
(102838-260)
Supplier:
Matrix Scientific
Description:
(3S,4S)-1-(tert-Butoxycarbanyl)-4-isopropylpyrrolidine-3-carboxylic acid ≥97%
Catalog Number:
(101940-660)
Supplier:
Matrix Scientific
Description:
2-Amino-5-Bromothiazole Hydrobromide, MF=C3H4Br2N2S MW=259.96 CAS: 61296-22-8 MDL=MFCD00012712 25G
Supplier:
AMBEED, INC
Description:
2-Bromo-6-methoxybenzothiazole, Purity: 95%, CAS number: 2941-58-4, Appearance: Pale-yellow to Yellow-brown or Red Solid, Storage: Inert atmosphere, 2-8C, Size: 5G
Supplier:
TCI America
Description:
Ethyl 2-(2-Amino-4-Thiazolyl)-2-Oxoacetate, Purity: >96.0%(HPLC)(T), Cas no: 64987-08-2, Molecular formula : C7H8N2O3S, Molecular weight : 200.21, Synonyms: 2-(2-Amino-4-thiazolyl)-2-oxoacetic Acid Ethyl Ester, Size: 25G
Supplier:
Adipogen
Description:
Quizartinib (AC220) is a second-generation FLT3 inhibitor that has shown promising activity in AML in Phase II clinical trials. It inhibits mutant and wild-type FLT3 in vivo at 0.1 and 0.5µM, respectively, and has shown favorable activity and tolerability in phase I and II trials in acute myeloid leukemia, with QT prolongation as the dose-limiting toxicity. Recently, AC220 has also been shown to be an effective inhibitor of ATP-binding cassette (ABC) proteins ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein). Quizartinib inhibited transport of fluorescent ABCG2 and ABCB1 substrates in ABCG2- and ABCB1-overexpressing cells in a concentration-dependent manner, from 0.1 to 5µM and from 0.5 to 10µM, respectively, and inhibited-IAAP photolabeling of ABCG2 and ABCB1 with IC(50) values of 0.07 and 3.3µM, respectively.
Catalog Number:
(77242-286)
Supplier:
AMBEED, INC
Description:
2-(4-Phenylthiazol-2-yl)acetonitrile, Purity: 95%, CAS Number: 41381-89-9, Appearance: Brown to Red-brown Solid, Storage: Sealed in dry, Room Temperature, Size: 250mg
Catalog Number:
(TCM0065-25G)
Supplier:
TCI America
Description:
CAS Number: 96-53-7
MDL Number: MFCD00126013 Molecular Formula: C3H5NS2 Molecular Weight: 119.20 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 105
Supplier:
BeanTown Chemical
Description:
CAS: 693-13-0; EC No: 211-743-7; MDL No: MFCD00065689; RTECS: FF2175000
UN No: UN2929; Haz Class: 6.1 (3); Packing Group: II
Liquid; Linear Formula: (CH3)2CHN=C=NCH(CH3)2; Molecular Formula: C7H14N2; MW: 126.20
Boiling Point: 145-148°; Flash point: 31°C (89°F)
Density (g/mL): 0.815; Refractive Index: 1.433
Moisture Sensitive
Catalog Number:
(TCD3549-5G)
Supplier:
TCI America
Description:
CAS Number: 4175-76-2
MDL Number: MFCD08691358 Molecular Formula: C3HCl2NS Molecular Weight: 154.01 Purity/Analysis Method: >98.0% (GC) Form: Crystal Boiling point (°C): 184 Melting point (°C): 44
Supplier:
AMBEED, INC
Description:
2,5-Dibromothiazole, Purity: 97%, CAS Number: 4175-78-4, Appearance: Solid or Semi-solid or liquid or lump, Storage: Inert atmosphere, Room Temperature, Size: 25g
Supplier:
AMBEED, INC
Description:
(2-Methylthiazol-5-yl)methanol, Purity: 95%, CAS Number: 56012-38-5, Appearance: Solid or semi-solid or lump or liquid, Storage: Sealed in dry, 2-8C, Size: 5G
Supplier:
AMBEED, INC
Description:
2-Amino-5-bromo-4-methylthiazole hydrochloride, Purity: 98%, CAS Number: 133692-16-7, Appearance: Form: solid, Storage: Inert atmosphere, Room Temperature, Size: 5g
Supplier:
AMBEED, INC
Description:
2-Phenylthiazole-4-carboxylic acid, Purity: 95%, CAS Number: 7113-10-2, Appearance: White to yellow powder or crystals, Storage: Sealed in dry, Room Temperature, Size: 250mg
Supplier:
TCI America
Description:
CAS Number: 15679-09-1
MDL Number: MFCD00085193 Molecular Formula: C5H7NS Molecular Weight: 113.18 Purity/Analysis Method: >98.0% (GC,T) Form: Clear Liquid Boiling point (°C): 148 Specific Gravity (20/20): 1.06
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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