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Thiomorpholine+1,1-dioxide+hydrochloride
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Thiomorpholine+1,1-dioxide+hydrochloride
Supplier:
AOB CHEM USA
Description:
(S)-2,2'-Dihydroxy-1,1'-binaphthalene-3,3'-diboronic acid pinacol ester ≥97%
Catalog Number:
(10229-636)
Supplier:
Bioss
Description:
Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. GLP-1 is a potent stimulator of glucose-dependent insulin release. Play important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Have growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion. Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation. Inhibits beta cell apoptosis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability. Oxyntomodulin significantly reduces food intake. Inhibits gastric emptying in humans. Suppression of gastric emptying may lead to increased gastric distension, which may contribute to satiety by causing a sensation of fullness. Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life.
Catalog Number:
(77437-882)
Supplier:
VWR
Description:
PIPES monosodium salt, clear, colorless, crystalline powder
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Appearance: Cream to yellow-brown Crystalline powder
Catalog Number:
(76194-746)
Supplier:
Prosci
Description:
The transcription factor Forkhead-box A1, also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. HNF-1 (alpha and beta), HNF-3 (alpha, beta and gamma), HNF-4 (alpha and gamma), and HNF-6 compose, in part, a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. Its expression correlates with estrogen receptor (ER)-positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. FOXA1 is useful in the sub-classification of breast carcinomas.
Catalog Number:
(101803-994)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 016062-500MG , MDL Number: MFCD03659710
Supplier:
AMBEED, INC
Description:
(E)-2,2'-(Fumaroylbis(oxy))bis(3,5-dibromobenzoic acid) 97%
Supplier:
AMBEED, INC
Description:
2,2'-Thiodisuccinic acid, Purity: 98%, CAS Number: 4917-76-4, Appearance: White to light-yellow solid, Storage: Sealed in dry, Room Temperature, Size: 25g
Catalog Number:
(76194-208)
Supplier:
Prosci
Description:
It recognizes a polypeptide of 6.5kDa, identified as pS2 estrogen-regulated protein. Its epitope is localized between aa57-84 of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.
Catalog Number:
(101846-730)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 039053-500MG , MDL Number: MFCD12027558
Catalog Number:
(101846-728)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 039052-500MG , MDL Number: MFCD12027557
Catalog Number:
(101846-792)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 039085-500MG , MDL Number: MFCD12027589
Catalog Number:
(AAH31852-06)
Supplier:
Thermo Scientific Chemicals
Description:
5g CAS: 28781-85-3, MDL: MFCD06657970
Catalog Number:
(101818-654)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 024692-1G , MDL Number: MFCD09800642
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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