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4-(2-Hydroxyethyl)cyclohexanol+(cis-+and+trans-+mixture)
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4-(2-Hydroxyethyl)cyclohexanol+(cis-+and+trans-+mixture)
Catalog Number:
(103265-388)
Supplier:
Southern Biotechnology
Description:
CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.
Catalog Number:
(10292-388)
Supplier:
Bioss
Description:
Cycling proteins play important roles in the organization and function of the early secretory pathway by participating in membrane traffic and selective transport of cargo between the endoplasmic reticulum (ER), the intermediate compartment (ERGIC), and the Golgi. A family of membrane bound, ubiquitous proteins involved in the selective transport of newly synthesized glycoproteins from the ER to the ERGIC include VIP36, ERGIC-53, ERGIC-1, ERGIC-2 and ERGIC-3. ERGIC-1, also designated ERGIC32, is thought to modulate the activity of a complex formed by ERGIC-2, also designated Erv41, and ERGIC-3, also designated Erv46. ERGIC-2 and ERGIC-3 are both mammalian homologs of yeast proteins abundant in COPII-coated vesicles and localize to the Cis-face of the Golgi apparatus.
Catalog Number:
(10292-400)
Supplier:
Bioss
Description:
Cycling proteins play important roles in the organization and function of the early secretory pathway by participating in membrane traffic and selective transport of cargo between the endoplasmic reticulum (ER), the intermediate compartment (ERGIC), and the Golgi. A family of membrane bound, ubiquitous proteins involved in the selective transport of newly synthesized glycoproteins from the ER to the ERGIC include VIP36, ERGIC-53, ERGIC-1, ERGIC-2 and ERGIC-3. ERGIC-1, also designated ERGIC32, is thought to modulate the activity of a complex formed by ERGIC-2, also designated Erv41, and ERGIC-3, also designated Erv46. ERGIC-2 and ERGIC-3 are both mammalian homologs of yeast proteins abundant in COPII-coated vesicles and localize to the Cis-face of the Golgi apparatus.
Supplier:
AMBEED, INC
Description:
(−)-Caryophyllene oxide 95%
Catalog Number:
(14214-926)
Supplier:
Epredia
Description:
The Eprediaâ„¢ Cal-Rite Decalcifing/Fixative Solution is a mixature of formic acid and formaldehyde which permits simultaneous decalcification and fixation.
Catalog Number:
(10303-850)
Supplier:
Bioss
Description:
The eight members of the recently identified Suppressor of Cytokines Signaling (SOCS) family are SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS6, SOCS7, and CIS. Structurally the SOCS proteins are composed of an N- terminal region of variable length and amino acid composition, a central SH2 domain, and a C-terminal motif called the SOCS box. The SOCS proteins appear to form part of a classical negative feedback loop that regulates cytokine signal transduction. Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways. During Th1 differentiation a reduction in the association of Jak1 with the IL4 Receptor correlated with the appearance of SOCS5. SOCS5 protein was preferentially expressed in committed Th1 cells and interacted with the cytoplasmic region of the IL4 Receptor alpha chain irrespective of receptor tyrosine phosphorylation. This unconventional interaction of SOCS5 protein with IL4 Receptor resulted in the inhibition of IL4-mediated signal transducer and activator of transcription-6 activation. T cells from transgenic mice constitutively expressing SOCS5 exhibited a significant reduction of IL4-mediated Th2 development. Therefore, the induced SOCS5 protein in Th1 differentiation environment may play an important role by regulating Th1 and Th2 balance.
Supplier:
BeanTown Chemical
Description:
CAS: 14592-56-4; EC No: 238-637-3; MDL No: MFCD00013122
UN No: UN3439; Haz Class: 6.1; Packing Group: III
Powder; Linear Formula: PdCl2(CH3CN)2; Molecular Formula: C4H6Cl2N2Pd; MW: 259.43
Catalog Number:
(EM8.01801.1000)
Supplier:
AMBEED, INC
Description:
(2S,5R)-2-Isopropyl-5-methylcyclohexanone, Purity: 90% GC, CAS Number: 14073-97-3, Appearance: Form: liquid Colour: colourless, Storage: Inert atmosphere, 2-8C, Size: 500G
Supplier:
AMBEED, INC
Description:
Methylene blue trihydrate 97%
Catalog Number:
(10069-094)
Supplier:
Prosci
Description:
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a member of the hnRNP A/B family of related RNA binding proteins that bind pre-mRNA and are involved in the processing, metabolism and transport of nuclear pre-mRNA transcripts. hnRNP A1 regulates the alternative splicing of c-Src, c-H-Ras and modifies initiation of translation of the fibroblast growth factor 2 mRNA. hnRNP A1 expression level is elevated in many cancers; knockdown of hnRNP A1 leads to apoptosis in various cancer cells. Although predominantly nuclear, hnRNP A1 is continually transported from the nucleus to the cytoplasm where it disassociates from mRNA and is rapidly re-imported into the nucleus. hnRNP A1 binds to cis-acting repressive sequences (CRS) of HIV-1 to influence HIV-1 production. HIV-1 enhances hnRNP A1 expression and promotes the relocalization of hnRNP A1 to the cytoplasm ,
Catalog Number:
(76109-732)
Supplier:
Bioss
Description:
Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity).
Catalog Number:
(EM8.24449.0250)
Supplier:
MilliporeSigma
Description:
(1R, 2R)-(-)-1, 2-Cyclohexanedicarboxylic acid, CAS no : 46022-05-3, Synonyms (1R, 2R)-(-)-Hexahydrophthalic acid, for synthesis, 250mg
Catalog Number:
(82024-256)
Supplier:
GE Healthcare - HyClone
Description:
Trypan Blue solution, 0,4%, is routinely used as a cell stain to assess cell viability using the dye exclusion test.
Supplier:
RPI
Description:
Methylene blue trihydrate
Supplier:
Matrix Scientific
Description:
MF=C7H8N2O2 MW=152.15 CAS=99-55-8 MDL=MFCD00007741 100G
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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