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1,4-Dibromo-2-(difluoromethoxy)benzene
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1,4-Dibromo-2-(difluoromethoxy)benzene
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
L(+)-Asparagine monohydrate, meets analytical specification of Ph.Eur.
Supplier:
Bachem Americas
Description:
Mix of τ-Bzl (mainly formed) and π-Bzl isomer. CAS Numbers: 16832-24-9 (τ-isomer), 26086-41-9 (π-isomer).
Supplier:
AMBEED, INC
Description:
N-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide, Purity: 98%, CAS Number: 616880-14-9, Appearance: Form: solid Colour: white to pink, Storage: Sealed in dry, 2-8C, Size: 5G
Supplier:
Diagnostic Biosystems
Description:
Clone number XM26&LL002, This antibody cocktail reacts with cytokeratin 5 intermediate filament protein as well as to 50 kD cytokeratin protein designated cytokeratin 14. Basal cells of human epidermis express acidic cytokeratin 14 and basic cytokeratin 5. Cytokeratin 5 is a 58 kD protein, which is closely related to cytokeratin 6. .
Supplier:
AMBEED, INC
Description:
5''-(3',5'-Dicarboxy-[1,1'-biphenyl]-4-yl)-[1,1':4',1'':3'',1''':4''',1''''-quinquephenyl]-3,3'''',5,5''''-tetracarboxylic acid, Purity: 98%, CAS Number: 1126896-14-7, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 100MG
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Atorvastatin (3S,5R) Isomer Calcium Salt (Atorvastatin USP Related Compound B), TLC Pharmaceutical Standards
Catalog Number:
(AAJ66639-MC)
Supplier:
Thermo Scientific Chemicals
Description:
Sarafloxacin hydrochloride hydrate, 98%
Supplier:
ZING Enterprises
Description:
The sign is available in 2 sizes, 7 x 10", and 10 x 14", and three eco-friendly formats.
Catalog Number:
(10468-544)
Supplier:
Bioss
Description:
Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.
Catalog Number:
(75933-596)
Supplier:
Rockland Immunochemical
Description:
The sorting of acid hydrolases to lysosomes rely on mannose 6-phosphate receptors that cycle between the trans-Golgi network (TGN) and endosomes. The maintenance of this cycle requires the function of the mammalian Golgi-associated retrograde protein (GARP) complex which is composed of three subunits: VPS52, VPS53, and VPS54. Depletion of any of these three proteins, such as by RNAi, impairs the retrograde transport of multiple TGN proteins. VPS53 was identified as an HIV dependency factor (HDF) and plays a role in viral entry to the cell, suggesting that VPS53 may be an important drug target in HIV treatment. At least five isoforms of VPS53 are known to exist.
Supplier:
AMBEED, INC
Description:
Cilnidipine 98%
Catalog Number:
(10303-850)
Supplier:
Bioss
Description:
The eight members of the recently identified Suppressor of Cytokines Signaling (SOCS) family are SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS6, SOCS7, and CIS. Structurally the SOCS proteins are composed of an N- terminal region of variable length and amino acid composition, a central SH2 domain, and a C-terminal motif called the SOCS box. The SOCS proteins appear to form part of a classical negative feedback loop that regulates cytokine signal transduction. Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways. During Th1 differentiation a reduction in the association of Jak1 with the IL4 Receptor correlated with the appearance of SOCS5. SOCS5 protein was preferentially expressed in committed Th1 cells and interacted with the cytoplasmic region of the IL4 Receptor alpha chain irrespective of receptor tyrosine phosphorylation. This unconventional interaction of SOCS5 protein with IL4 Receptor resulted in the inhibition of IL4-mediated signal transducer and activator of transcription-6 activation. T cells from transgenic mice constitutively expressing SOCS5 exhibited a significant reduction of IL4-mediated Th2 development. Therefore, the induced SOCS5 protein in Th1 differentiation environment may play an important role by regulating Th1 and Th2 balance.
Supplier:
BeanTown Chemical
Description:
CAS: 7647-01-0; EC No: 231-595-7; MDL No: MFCD00011324
UN No: UN2924; Haz Class: 3(8); Packing Group: II
Liquid; Molecular Formula: HCl; MW: 36.46
Flash point: 17°C (63°F)
Density (g/mL): 1.05
Hygroscopic
Supplier:
TCI America
Description:
CAS Number: 130-14-3
MDL Number: MFCD00064964 Molecular Formula: C10H8O3S Molecular Weight: 230.21 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal
Supplier:
TCI America
Description:
CAS Number: 17265-14-4
MDL Number: MFCD00070501 Molecular Formula: C10H18O4 Molecular Weight: 246.21 Purity/Analysis Method: >97.0% (T) Form: Crystal Color: White
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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