4-(Di-p-tolylamino)benzaldehyde
Supplier:
AMBEED, INC
Description:
Tricine 98%
Supplier:
Leica Biosystems
Description:
Gas adaptor plate for adult mice and rats
Catalog Number:
(10296-494)
Supplier:
Bioss
Description:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
Supplier:
Thermo Scientific Chemicals
Description:
Carbonylation, oxidation and C-C bond formation
Catalog Number:
(102096-958)
Supplier:
Electron Microscopy Sciences
Description:
Easy microplate viewing for pipetting and liquid transfer.
Catalog Number:
(102097-018)
Supplier:
Electron Microscopy Sciences
Description:
Used for working comfortably with solid state media.
Supplier:
Transene
Description:
Transene Hexamethyldisilzane LM (HMDS) is an ultra-high purity, "low metals" adhesion promoter for photoresists and other photolithography applications.
Catalog Number:
(10049-378)
Supplier:
Enzo Life Sciences
Description:
Acetylation and methylation of lysine are important post-translational modifications that regulate numerous protein-protein and protein-DNA interactions. Lysine acetylation and methylation involves the transfer of acetylCoA, or one or more methyl groups, to the e-amino group of lysine by modifying enzymes and cofactors. Histones and transcription factors are the primary targets of lysine acetylation and methylation, with either modification capable of inducing gene silencing or expression due to differential regulation of cofactors. For example, varying degrees of mono-, di-, and tri-methylation or acetylation of histone H3 at lysine residue 9 are known to demark distinct chromatin regions during various states of gene activation (methylation) or repression (acetylation).
Catalog Number:
(10148-974)
Supplier:
Immunoreagents
Description:
ImmunoReagents Goat IgG Affinity Prep resins are prepared using highly purified species specific immunoglobulins
Catalog Number:
(10148-970)
Supplier:
Immunoreagents
Description:
ImmunoReagents Chicken IgY Affinity Prep resins are prepared using highly purified species specific immunoglobulins
Supplier:
KYFORA BIO LLC.
Description:
Transfection reagents for eukaryotic cells.
Catalog Number:
(10799-908)
Supplier:
Rockland Immunochemical
Description:
BRSK1 was initially identified as a mammalian homolog to the fission yeast S. pombe Cdr2, a mitosis-regulatory kinase and also shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK1 is unbiquitously expressed, with highest levels of expression in the brain and testes. Similar to its yeast homolog, BRSK1 is thought to be involved in stress-induced cell cycle arrest. Overexpression of this protein leads to the G2/M arrest in HeLa S2 cells and UV-induced G2/M arrest could be partially abrogated by reduced expression of BRSK1 through the use of siRNA, indicating its role in DNA damage checkpoint function. More recently, it has been shown that both BRSK1 and the related protein BRSK2 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. At least two isoforms of BRSK1 are known to exist.
Supplier:
BeanTown Chemical
Description:
CAS: 20667-12-3; EC No: 243-957-1; MDL No: MFCD00003404; RTECS: VW4900000
UN No: UN1479; Haz Class: 5.1; Packing Group: II
Powder; Molecular Formula: Ag2O; MW: 231.74
Melting Point: 230° (decomposes)
Density (g/mL): 7.143
Light Sensitive
Supplier:
Invitrogen
Description:
Thermo Scientific Pierce Glutathione Superflow Agarose consists of glutathione that has been immobilized to a crosslinked 6% beaded agarose that is designed for high-purity, large-scale purification of GST-tagged proteins.
Supplier:
Mirus Bio
Description:
High performance - provide higher functional titers. Animal origin free - regulatory friendly.
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