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Necrox-5\\\\u2122+methanesulfonate
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Necrox-5\\\\u2122+methanesulfonate
Supplier:
AOB CHEM USA
Description:
2-Chloro-6-methylphenylboronic acid ≥95%
Supplier:
MP Biomedicals
Description:
Protein kinase C inhibitor (IC50 = 50-200 µM depending on assay conditions in MCF-7 cells or IC50 = 100 µM in rat brain). The PKC inhibition is also dependent on the phosopholipid concentration. Also inhibits both calmodulin-dependent and calmodulin-independent Ca2+-, Mg2+-ATPase. Tamoxifen is a selective estrogen response modifier (SERM), anti-angiogenetic factor. It is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Catalog Number:
(80054-462)
Supplier:
MilliporeSigma
Description:
Nitric oxide (NO) donor. Spontaneously decomposes to yield NO and superoxide anion radicals. Also inhibits release of plasminogen activator inhibitor (PAI) from stimulated platelets. CAS: 16142-27-1.FW: 206.7. Purity: >= 98% by TLC. Soluble in DMSO, ethanol and water. 20mg white solid.
Supplier:
Adipogen
Description:
Free coumarin-3-carboxylic acid shows a stronger fluorescence (Em. max: 419 nm (Exc.: 366 nm in ethanol).
Supplier:
Spectrum Chemicals
Description:
m-Cresol Purple, also known as m-Cresolsulfonphthalein, is a pH indicator dye used primarily in spectrophotometric pH measurements. m-Cresol purple is acidic and hydrophobic. The useful pH ranges are 1.2 - 2.8 (red to yellow) and 7.4 - 9.0 (yellow to violet).
Catalog Number:
(76924-324)
Supplier:
AOB CHEM USA
Description:
4-Formyl-2-methylphenylboronic acid ≥97%
Catalog Number:
(80052-248)
Supplier:
MilliporeSigma
Description:
A major aldehydic product formed by peroxidation of [omega]-6-unsaturated fatty acids
Catalog Number:
(TCT1997-5G)
Supplier:
TCI America
Description:
CAS Number: 86259-87-2
MDL Number: MFCD06797175 Molecular Formula: C15H24O5 Molecular Weight: 284.35 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Color: Very Pale Yellow Specific Gravity (20/20): 1.10
Catalog Number:
(71000-200)
Supplier:
Ace Glass
Description:
These wide mouth safety wash bottles are guaranteed to be leak-proof.
Supplier:
TCI America
Description:
CAS Number: 875-59-2
Molecular Formula: C9H10O2 Molecular Weight: 150.18 Purity/Analysis Method: >98.0% (GC) Form: Crystal Boiling point (°C): 313 Melting point (°C): 130
Catalog Number:
(AAH52752-03)
Supplier:
Thermo Scientific Chemicals
Description:
1g CAS: 163517-61-1, MDL: MFCD07368679
Supplier:
Matrix Scientific
Description:
MF=C8H8F2O MW=158.15 MDL=MFCD01631335 1G
Catalog Number:
(PAG1751)
Supplier:
Promega Corporation
Description:
This conventional DNA digest marker is generated by ΦX174 DNA digested to completion with HinfI to create 20 ethanol-precipitated DNA fragments ranging in size from 24bp to 726bp.
Supplier:
Matrix Scientific
Description:
MF=C7H11CLN2 MW=158.63 CAS=637-60-5 MDL=MFCD00012940 25G
Supplier:
MP Biomedicals
Description:
Tris have been useful as buffers in a wide variety of biological systems. It has been used as a starting material for polymers, oxazolones (with carboxylic acids) and oxazolidines (with aldehydes). It does not precipitate calcium salts and is of value in maintaining solubility of manganese salts. It can be used for the direct standardization of a strong acid solution; the equivalence point can be determined either potentiometrically or by use of a suitable indicator such as 3-(4-Dimethylamino-1-naphthylazo)-4-methoxybenzenesulfonic acid. It is RNAse and DNAse-free. Tris is relatively non-hygroscopic ; but, if needed, it can be dried at 100 °C for up to 4 hours to remove any water.
Tris is used in pH control in vitro and in vivo for body fluids and in buffering systems for electrophoresis applications.Tris is used in assays used to characterize the activity and kinetics of the enzymes that catalyze SUMOylation of Small ubiquitin-like proteins (SUMO) and SUMO-dependent protein-protein interactions.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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