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N-Benzoyl-2\'-deoxyadenosine
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N-Benzoyl-2\'-deoxyadenosine
Catalog Number:
(10276-638)
Supplier:
Bioss
Description:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF426 (Zinc finger protein 426), also known as MGC2663, is a 554 amino acid protein that is thought to be involved in transcriptional regulation. Localized to the nucleus, ZNF426 contains one KRAB domain and 12 C2H2-type zinc fingers through which it may convey DNA, RNA and protein binding capabilities. Specifically, ZNF426 may interact with the viral protein KSHV ORF 50 and, through this interaction, may activate viral gene transcription.
Supplier:
AMBEED, INC
Description:
Bortezomib 98%
Catalog Number:
(101942-548)
Supplier:
Matrix Scientific
Description:
MF=C5H8Brcln4 MW=239.51 Cas=903130-08-5 ,5G
Catalog Number:
(10321-750)
Supplier:
Bioss
Description:
This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.
Catalog Number:
(10800-208)
Supplier:
Rockland Immunochemical
Description:
Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). ATG4A, also known as AUTL2, is one of four mammalian orthologs of the yeast ATG4 protein; all four are cysteine proteases (3). ATG4 is required for ATG8 conjugation to phosphatidylethanolamine on autophagosomal membranes. In mammals, each ATG4 homolog shows a selective preference for the ATG8 homologs (4).
Catalog Number:
(76214-708)
Supplier:
Ansell Healthcare
Description:
Multi-layer barrier laminate construction.
Catalog Number:
(101933-874)
Supplier:
Matrix Scientific
Description:
MF=C12H18Cln3O2S MW=303.81 250Mg
Supplier:
AMBEED, INC
Description:
Acalabrutinib 98%
Catalog Number:
(101935-834)
Supplier:
Matrix Scientific
Description:
2-Methyl-6-Pyrrolidin-2-Yl-Pyrazine Dihydrochloride, MF=C9H15Cl2N3 MW=236.15 250Mg
Supplier:
Adipogen
Description:
Cell permeable, selective and irreversible IKKalpha and beta kinase activity inhibitor. NF-kappaB inhibitor. Blocks phosphorylation and degradation of IkappaBalpha. Antihepatotoxic. 5-Lipoxygenase (5-LOX) inhibitor. Anti-inflammatory. HIV-1 integrase inhibitor. Anticancer and antiproliferative compound. Modulates androgen receptor (AR) activation. Apoptosis inducer via downregulation of PKCepsilon. DNA topoisomerase IIalpha inhibitor. G protein-coupled receptor-35 (GPR35) agonist. Inhibits adipogenic differentiation of mesenchymal stem cells (hAMSCs) through ERK pathway. STAT1 protein dephosphorylation inhibitor. Antifibrotic.
Supplier:
AMBEED, INC
Description:
6-(4-Amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine hydrochloride, Purity: 98+%, CAS Number: 1801747-11-4, Appearance: Solid, Storage: Inert atmosphere, Store in freezer, under -20 C, Size: 10mg
Supplier:
AMBEED, INC
Description:
MK 212 HCl 98%
Supplier:
AMBEED, INC
Description:
1-(6-Chloro-2-pyrazinyl)-4-methylpiperazine 95%
Catalog Number:
(10062-046)
Supplier:
Prosci
Description:
The G protein–coupled receptor kinases (GRKs) are a versatile family of kinases that play a critical role in cancer metastasis through their regulation of G-protein coupled receptors (GPCRs) involved in growth factor mediated cell migration (1,2). Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state. GRK6 is one of 7 members of the GRK serine/threonine kinase subfamily, which has been shown to modulate the Wnt signaling pathway via phosphorylation of LRP6 (3,4), and the insulin-like growth factor signaling pathway. GRK6 may also play a role in immune system function.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 042999-5G , MDL Number: MFCD00662755
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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