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2-Chloroadenosine+hemihydrate
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2-Chloroadenosine+hemihydrate
Supplier:
ALADDIN SCIENTIFIC
Description:
Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Target: NRTIs; HBV Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Adefovir Dipivoxil is used for treatment of hepatitis B and herpes simplex virus infection [1-3]. Adefovir Dipivoxil is approved for the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (primarily ALT) or histologically active disease. Adefovir Dipivoxil is a failed treatment for HIV[3, 4]. Catalyst employed in the Sharpless Asymmetric Dihyroxylation of (E,E)- or (E,Z)-1,3-dienoates.1 Also used in the preparation of ?-hydroxy-γ-lactones from ?,γ-unsaturated esters.2Product Introduction:Adefovir dipivoxil, an adenosine analogue, is an oral proagent of the nucleoside reverse transcriptase inhibitor Adefovir. Adefovir dipivoxil inhibits both the wild type and HBV Lamivudine-resistant strains. Adefovir dipivoxil shows anti-orthopoxvirus activity.
Catalog Number:
(102853-278)
Supplier:
Matrix Scientific
Description:
tert-Butyl-4-{[8-(ethoxycarbonyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]methyl}piperidine-1-carboxylate ≥97%
Catalog Number:
(TS194982500)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Bis(2-butoxyethyl)ether 99+%, pure
Catalog Number:
(TCB1019-100G)
Supplier:
TCI America
Description:
CAS Number: 574-09-4
MDL Number: MFCD00009242 Molecular Formula: C16H16O2 Molecular Weight: 240.30 Purity/Analysis Method: >99.0% (GC) Form: Crystal Boiling point (°C): 125 Melting point (°C): 61 Flash Point (°C): 153
Supplier:
TCI America
Description:
CAS Number: 111-90-0
MDL Number: MFCD00002872 Molecular Formula: C6H14O3 Molecular Weight: 134.18 Purity/Analysis Method: >99.0% (GC) Form: Clear Liquid Boiling point (°C): 196 Flash Point (°C): 96 Specific Gravity (20/20): 0.99
Supplier:
BeanTown Chemical
Description:
CAS: 112-73-2; EC No: 204-001-9; MDL No: MFCD00009459; RTECS: KN0350000
Liquid; Linear Formula: [CH3(CH2)3OCH2CH2]2O; Molecular Formula: C12H26O3; MW: 218.33
Melting Point: -60°; Boiling Point: 256°; Flash point: 118°C (244°F)
Density (g/mL): 0.885; Refractive Index: 1.423
Supplier:
BeanTown Chemical
Description:
CAS: 10031-82-0; EC No: 233-093-3; MDL No: MFCD00003388; RTECS: CU6100000
Liquid; Molecular Formula: C9H10O2; MW: 150.18
Melting Point: 13-14°; Boiling Point: 255°; Flash point: <gt/>110°C (<gt/>230°F)
Density (g/mL): 1.08; Refractive Index: 1.559
Air Sensitive
Supplier:
TCI America
Description:
CAS Number: 143-22-6
MDL Number: MFCD00020606 Molecular Formula: C10H22O4 Molecular Weight: 206.28 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Color: Colorless Boiling point (°C): 278 Melting point (°C): -35 Flash Point (°C): 156 Specific Gravity (20/20): 0.99
Catalog Number:
(ALA129352250MG)
Supplier:
ALADDIN SCIENTIFIC
Description:
Ampiroxicam is a nonselective cyclooxygenase inhibitor which has anti-inflammatory effects.a COX-1 and COX-2 inhibitor
Supplier:
AMBEED, INC
Description:
Diethylene Glycol Monoethyl Ether, Purity: 99%, CAS Number: 111-90-0, Appearance: Colorless to almost colorless liquid, Storage: Inert atmosphere, Room Temperature, Size: 100G
Supplier:
AAT BIOQUEST INC
Description:
Among the ratiometric calcium indicators, Fura-2 and Indo-1 are most commonly used.
Supplier:
TCI America
Description:
CAS Number: 112-73-2
MDL Number: MFCD00009459 Molecular Formula: C12H26O3 Molecular Weight: 218.34 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 255 Melting point (°C): -60 Flash Point (°C): 122 Specific Gravity (20/20): 0.88
Supplier:
TCI America
Description:
CAS Number: 78-10-4
MDL Number: MFCD00009062 Molecular Formula: C8H20O4Si Molecular Weight: 208.33 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Color: Colorless Boiling point (°C): 165 Melting point (°C): -82 Flash Point (°C): 54 Specific Gravity (20/20): 0.93
Supplier:
AMBEED, INC
Description:
N-(3-((2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl)oxy)phenyl)-4-(2-morpholinoethoxy)benzamide, Purity: 98%, CAS Number: 850664-21-0, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 5mg
Supplier:
Bachem Americas
Description:
Sequence: Fmoc-D-Tyr(Et)-OH
Catalog Number:
(77439-970)
Supplier:
Bioss
Description:
Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses. Upon DNA damage, activates the promoter of the death-promoting transcription factor BCLAF1/Btf to trigger BCLAF1-mediated p53/TP53 gene transcription and apoptosis. In response to oxidative stress, interact with and activate CHUK/IKKA in the nucleus, causing the phosphorylation of p53/TP53. In the case of ER stress or DNA damage-induced apoptosis, can form a complex with the tyrosine-protein kinase ABL1 which trigger apoptosis independently of p53/TP53. In cytosol can trigger apoptosis by activating MAPK11 or MAPK14, inhibiting AKT1 and decreasing the level of X-linked inhibitor of apoptosis protein (XIAP), whereas in nucleus induces apoptosis via the activation of MAPK8 or MAPK9. Upon ionizing radiation treatment, is required for the activation of the apoptosis regulators BAX and BAK, which trigger the mitochondrial cell death pathway. Can phosphorylate MCL1 and target it for degradation which is sufficient to trigger for BAX activation and apoptosis. Is required for the control of cell cycle progression both at G1/S and G2/M phases. Mediates phorbol 12-myristate 13-acetate (PMA)-induced inhibition of cell cycle progression at G1/S phase by up-regulating the CDK inhibitor CDKN1A/p21 and inhibiting the cyclin CCNA2 promoter activity. In response to UV irradiation can phosphorylate CDK1, which is important for the G2/M DNA damage checkpoint activation. Can protect glioma cells from the apoptosis induced by TNFSF10/TRAIL, probably by inducing increased phosphorylation and subsequent activation of AKT1. Is highly expressed in a number of cancer cells and promotes cell survival and resistance against chemotherapeutic drugs by inducing cyclin D1 (CCND1) and hyperphosphorylation of RB1, and via several pro-survival pathways, including NF-kappa-B, AKT1 and MAPK1/3 (ERK1/2). Can also act as tumor suppressor upon mitogenic stimulation with PMA or TPA. In N-formyl-methionyl-leucyl-phenylalanine (fMLP)-treated cells, is required for NCF1 (p47-phox) phosphorylation and activation of NADPH oxidase activity, and regulates TNF-elicited superoxide anion production in neutrophils, by direct phosphorylation and activation of NCF1 or indirectly through MAPK1/3 (ERK1/2) signaling pathways. May also play a role in the regulation of NADPH oxidase activity in eosinophil after stimulation with IL5, leukotriene B4 or PMA. In collagen-induced platelet aggregation, acts a negative regulator of filopodia formation and actin polymerization by interacting with and negatively regulating VASP phosphorylation. Downstream of PAR1, PAR4 and CD36/GP4 receptors, regulates differentially platelet dense granule secretion; acts as a positive regulator in PAR-mediated granule secretion, whereas it negatively regulates CD36/GP4-mediated granule release. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.
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is still displayed and you need assistance, please call us at 1-800-932-5000.
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