5-Chloro-4-(trifluoromethyl)picolinonitrile
Supplier:
AMBEED, INC
Description:
Ethyl 3-methylbenzoate, Purity: 99%, CAS Number: 120-33-2, Appearance: Colorless to Yellow Liquid, Storage: Sealed in dry, Room Temperature, Size: 1g
Supplier:
AOB CHEM USA
Description:
Ethyl-3-chlorobenzoylformate ≥97%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Ethyl chloroformate 99%, AcroSeal™
Catalog Number:
(102995-432)
Supplier:
Cell Sciences
Description:
Flow Cytometry: Use 10 µl to label 10E6 cells or 100 µl of whole blood.
Supplier:
AMBEED, INC
Description:
N-(2-((4-Amino-3-methylphenyl)(ethyl)amino)ethyl)methanesulfonamide sulfate(2:3) 95%
Supplier:
VWR
Description:
Commonly used stain for the detection of protein bands following electrophoresis.
Supplier:
AMBEED, INC
Description:
Ethyl 2-amino-2-(hydroxyimino)acetate, Purity: 98%, CAS Number: 10489-74-4, Appearance: Form: solid, Storage: Keep in dark place, Inert atmosphere, 2-8C, Size: 100G
Supplier:
AMBEED, INC
Description:
Ethyl-4-fluoro-3-nitrobenzoate 98%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Ethyl-6-chloro-3-pyridazinecarboxylate 95%
Supplier:
TCI America
Description:
CAS Number: 4244-84-2
MDL Number: MFCD00012909 Molecular Formula: C5H11NO2 Molecular Weight: 153.61 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 69
Catalog Number:
(10234-564)
Supplier:
Bioss
Description:
The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit (95 kDa) possesses a single transmembrane domain, whereas the alpha subunit (135 kDa) is completely extracellular. The insulin receptor exhibits receptor tyrosine kinase (RTK) activity. RTKs are single pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the gamma phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that affect cell proliferation, differentiation, migration and metabolism.Included in this large protein family are the insulin receptor and the receptors for growth factors such as epidermal growth factor, fibroblast growth factor and vascular endothelial growth factor. Receptor activation occurs through ligand binding, which facilitates receptor dimerization and autophosphorylation of specific tyrosine residues in the cytoplasmic portion. The interaction of insulin with the alpha subunit of the insulin receptor activates the protein tyrosine kinase of the beta subunit, which then undergoes an autophosphorylation that increases its tyrosine kinase activity. Three adapter proteins, IRS1, IRS2 and Shc, become phosphorylated on tyrosine residues following insulin receptor activation. These three phosphorylated proteins then interact with SH2 domain containing signaling proteins.
Catalog Number:
(10326-436)
Supplier:
Bioss
Description:
Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The cytokeratins are encoded by a family encompassing 30 genes. Among them, 20 are epithelial genes and the remaining 10 are specific for trichocytes.
In the cytoplasm, the keratin filaments conform a complex network which extends from the surface of the nucleus to the cell membrane. Numerous accessory proteins are involved in the genesis and maintenance of such structure. This association between the plasma membrane and the nuclear surface provides important implications for the organization of the cytoplasm and cellular communication mechanisms. Apart from the relatively static functions provided in terms of supporting the nucleus and providing tensile strength to the cell, the cytokeratin networks undergo rapid phosphate exchanges mediated depolymerization, with important implications in the more dynamic cellular processes such as mitosis and post-mitotic period, cell movement and differentiation. Cytokeratins interact with desmosomes and hemidesmosomes, thus collaborating to cell-cell adhesion and basal cell-underlying connective tissue connection.
Catalog Number:
(10284-390)
Supplier:
Bioss
Description:
There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.
Supplier:
AMBEED, INC
Description:
Ethyl benzoylformate, Purity: 95%, CAS Number: 1603-79-8, Appearance: Form: liquid / Colour: Colorless - Yellow, Storage: Inert atmosphere, Room Temperature, Size: 25G
Supplier:
AMBEED, INC
Description:
Ethyl-4-oxazolecarboxylate 97%
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