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Supplier:
AMBEED, INC
Description:
(6-Bromobenzo[d][1,3]dioxol-5-yl)methanol, Purity: 95%, CAS Number: 6642-34-8, Appearance: White to off-white powder or crystals, Storage: Sealed in dry, Room Temperature, Size: 100mg
Supplier:
AMBEED, INC
Description:
5-Bromo-2,1,3-benzothiadiazole 95%
Supplier:
Adipogen
Description:
Quizartinib (AC220) is a second-generation FLT3 inhibitor that has shown promising activity in AML in Phase II clinical trials. It inhibits mutant and wild-type FLT3 in vivo at 0.1 and 0.5µM, respectively, and has shown favorable activity and tolerability in phase I and II trials in acute myeloid leukemia, with QT prolongation as the dose-limiting toxicity. Recently, AC220 has also been shown to be an effective inhibitor of ATP-binding cassette (ABC) proteins ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein). Quizartinib inhibited transport of fluorescent ABCG2 and ABCB1 substrates in ABCG2- and ABCB1-overexpressing cells in a concentration-dependent manner, from 0.1 to 5µM and from 0.5 to 10µM, respectively, and inhibited-IAAP photolabeling of ABCG2 and ABCB1 with IC(50) values of 0.07 and 3.3µM, respectively.
Catalog Number:
(101919-462)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 059925-1G , MDL Number: MFCD09878605
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 059546-500MG , MDL Number: MFCD12032270
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 064066-500MG , MDL Number: MFCD19381762
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
5-Bromo-1,3-benzodioxole 97%
Supplier:
Matrix Scientific
Description:
MF=C8H6BRNO4 MW=260.05 CAS=2363-16-8 MDL=MFCD00553089 5G
Supplier:
AMBEED, INC
Description:
N-Bromosaccharin 98%
Supplier:
AMBEED, INC
Description:
Methyl 2,3-diamino-5-bromobenzoate, Purity: 97%, CAS Number: 1248541-63-0, Appearance: Yellow to Brown Solid, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 250mg
Supplier:
AMBEED, INC
Description:
5-Bromo-(2,3-methylenedioxy)phenylboronic acid pinacol ester 98%
Supplier:
AMBEED, INC
Description:
3-Bromo-1,8-naphthalic anhydride 95%
Supplier:
AMBEED, INC
Description:
5-Bromobenzofuran, Purity: 97%, CAS Number: 23145-07-5, Appearance: Liquid or solid, Storage: Sealed in dry, Room Temperature, Size: 500g
Supplier:
AMBEED, INC
Description:
7-Bromobenzo[c][1,2,5]thiadiazole-4-carbaldehyde, Purity: 97%, CAS Number: 1071224-34-4, Appearance: Form: Crystal - Powder/Colour: White - Yellow, Storage: Inert atmosphere, Room Temperature, Size: 250mg
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 024631-25G , MDL Number: MFCD00007823
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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