5-(Ethoxymethyl)pyridine-3-boronic+acid
Catalog Number:
(76009-962)
Supplier:
Prosci
Description:
TDRD7, also known as Tudor domain containing protein 7, is a component of chromatoid bodies in spermatids (named processing bodies or P-bodies in somatic cells). It is found in a mRNP complex together with TDRD1, TDRD6 and DDX4. It is also found in a complex with CABLES1, PCTK2 and PIWIL1. TDRD7 has been shown to interact with histone H3 tri-methylated at K9 in vitro.
Supplier:
BeanTown Chemical
Description:
CAS: 3618-43-7; EC No: 222-805-8; MDL No: MFCD00044293
Powder; Molecular Formula: C31H28N2Na4O13S; MW: 760.59
Melting Point: 195° (decomposes)
Supplier:
Adipogen
Description:
XL765 is active against class I PI3K (IC(50) = 39, 113, 9 and 43nM for p110alpha, beta, gamma and delta, respectively). XL765 also inhibits DNA-PK (IC(50) = 150nM) and mTOR (IC(50) = 157nM)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Dibenzylamine 98%
Catalog Number:
(75935-220)
Supplier:
Rockland Immunochemical
Description:
ROCK1 is a member of the AGC serine/threonine protein kinase family that regulates the assembly of the actin cytoskeleton. ROCK1 contains a protein kinase domain, a coiled-coil region and a zinc finger region and appears to be present as a dimer. ROCK1, like its isozyme ROCK2, is a downstream target of the small G-protein Rho and plays a role in smooth muscle contraction, malignant cell transformation, tumor invasion and metastasis, and mediates the cellular morphological changes during apoptosis.
Catalog Number:
(103008-228)
Supplier:
Anaspec Inc
Description:
This peptide is Histone H3 with amino acid residues 69 to 89 di-methylated at Lys-79 with an additional C-terminal glycine followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:RLVREIAQDF-K(Me2)-TDLRFQSSAV-K(Biotin) MW:2862.3 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(76010-182)
Supplier:
Prosci
Description:
This gene encodes a protein that is related to methyl-CpG-binding proteins but lacks the methyl-CpG binding domain. The protein has been found in germ cell tumors and some somatic tissues.
Catalog Number:
(76080-300)
Supplier:
Bioss
Description:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
Catalog Number:
(10250-554)
Supplier:
Bioss
Description:
Prenylation and methylation are two forms of protein modification, both of which are important for a variety of functions, including membrane attachment, protein-protein interactions and signaling events. NARF (nuclear prelamin A recognition factor), also known as IOP2, is a 456 amino acid nuclear protein that belongs to the NARF family. Expressed ubiquitously with highest expression in heart, skeletal muscle and brain, NARF binds to the C-terminal end of prenylated prelamin A and may be a member of a prelamin A-containing endoprotease complex. Additionally, via its association with prelamin A, NARF may be involved in heterochromatin organization. NARF is expressed as three isoforms due to alternative splicing events and, upon DNA damage, may be phosphorylated by ATM or ATR.
Catalog Number:
(10667-360)
Supplier:
Bioss
Description:
Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.
Supplier:
MP Biomedicals
Description:
Formaldehyde is used as bactericidal agent. Formaldehyde is used as an embalming agent due to its ability to crosslink primary amino groups in proteins through a methylene linkage; however, due to its extremely toxic nature it tends to be avoided. Formaldehyde is also used in numerous industrial applications and organic syntheses.
Store at Room Temperature (15-30 °C)
Catalog Number:
(TCI0717-5G)
Supplier:
TCI America
Description:
CAS Number: 35944-64-0
MDL Number: MFCD00047843 Molecular Formula: C7H8IN Molecular Weight: 233.05 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Freezing point (°C): 32
Catalog Number:
(10749-344)
Supplier:
Prosci
Description:
Acinus Antibody: Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS'.
Supplier:
TCI America
Description:
CAS Number: 3734-33-6
MDL Number: MFCD00031578 Molecular Formula: C28H34N2O3 Molecular Weight: 446.59 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 163
Catalog Number:
(10414-020)
Supplier:
Bioss
Description:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
Supplier:
TCI America
Description:
CAS Number: 443-86-7
Molecular Formula: C7H8FN Molecular Weight: 125.15 Purity/Analysis Method: >98.0% (GC,T) Form: Clear Liquid Boiling point (°C): 205 Flash Point (°C): 86 Freezing point (°C): 1 Specific Gravity (20/20): 1.13
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