Potassium+hexachlororuthenate(III)
Supplier:
BeanTown Chemical
Description:
CAS: 35320-23-1; MDL No: MFCD00064413
UN No: UN2735; Haz Class: 8; Packing Group: III
Liquid; Linear Formula: CH3CH(NH2)CH2OH; Molecular Formula: C3H9NO; MW: 75.11
Boiling Point: 166-168°; Flash point: 83°C (181°F)
Density (g/mL): 0.963; Refractive Index: 1.449; Optical Rotation: [α]19/D −18°, neat
Air Sensitive , Hygroscopic
Catalog Number:
(10435-802)
Supplier:
Bioss
Description:
General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.
Catalog Number:
(RL000-119-200)
Supplier:
Rockland Immunochemical
Description:
20mg. Protein/Agarose: 10mg protein per cc agarose. Agarose/Suspension: 0.5cc agarose per mL of suspension. Buffer: 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2. Stabilizer: None. Preservative: 0.01% (w/v) sodium azide.
Catalog Number:
(76100-944)
Supplier:
Bioss
Description:
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which may have distinct functions.
Supplier:
BeanTown Chemical
Description:
CAS: 544-40-1; EC No: 208-870-5; MDL No: MFCD00009468; RTECS: ER6417000
UN No: UN3334; Haz Class: 9; Packing Group: III
Liquid; Linear Formula: CH3(CH2)3S(CH2)3CH3; Molecular Formula: C8H18S; MW: 146.29
Melting Point: -76°; Boiling Point: 188-189°; Flash point: 77°C (171°F)
Density (g/mL): 0.838; Refractive Index: 1.453
Catalog Number:
(102538-566)
Supplier:
Matrix Scientific
Description:
MF=C7H6N2S MW=150.20 CAS=136-95-8 MDL=MFCD00005785 100G
Supplier:
BeanTown Chemical
Description:
CAS: 718-64-9; EC No: 211-943-4; MDL No: MFCD00040983
UN No: UN1987; Haz Class: 3; Packing Group: III
Liquid; Molecular Formula: C9H6F6O; MW: 244.13
Boiling Point: 160°; Flash point: 60°C (140°F)
Density (g/mL): 1.45; Refractive Index: 1.415
Supplier:
BeanTown Chemical
Description:
CAS: 556-67-2; EC No: 209-136-7; MDL No: MFCD00003269; RTECS: GZ4397000
UN No: UN1993; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: [-Si(CH3)2O-]4; Molecular Formula: C8H24O4Si4; MW: 296.62
Melting Point: 71-18°; Boiling Point: 175-176°; Flash point: 55°C (131°F)
Density (g/mL): 0.956; Refractive Index: 1.396
Moisture Sensitive
Catalog Number:
(10357-820)
Supplier:
Bioss
Description:
Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma which plays a role in meiosis.
Supplier:
BeanTown Chemical
Description:
CAS: 10269-01-9; MDL No: MFCD01026119
UN No: UN2735; Haz Class: 8; Packing Group: III
Liquid; Molecular Formula: C7H8BrN; MW: 186.05
Supplier:
Seco Industries
Description:
These clear, zip-close static-shielding bags guarantee a secure closure that can be repeatedly opened and closed.
Catalog Number:
(10485-100)
Supplier:
Bioss
Description:
FNDC1, also known as MEL4B3, Ags8, Expressed in synovial lining protein and Activation-associated cDNA protein, is a 1888 amino acid secreted protein that contains five fibronectin type-III domains. FNDC1 is moderately expressed in skeletal muscle, pancreas, heart, kidney, spinal cord, ovary and lung. Expression of FNDC1 is induced in response to hypoxia in ventricular cardiomyocytes. Since FNDC1 interacts with G∫ and G©, it is likely that FNDC1 is an activator for G-protein signaling. Though normally absent in healthy skin, FNDC1 expression is induced by TGF-beta signaling in skin tumors and psoriasis. There are two isoforms of FNDC1 that are produced as a result of alternative splicing events.
Catalog Number:
(89296-738)
Supplier:
Genetex
Description:
Goat polyclonal antibody to KCNQ4
Supplier:
BeanTown Chemical
Description:
CAS: 317-34-0; EC No: 206-264-5; MDL No: MFCD00013221; RTECS: XH5600000
UN No: UN2811; Haz Class: 6.1; Packing Group: III
Powder; Molecular Formula: C7H8N4O2·0.5C2H8N2; MW: 210.21
Supplier:
BeanTown Chemical
Description:
CAS: 13446-18-9; EC No: 233-826-7; MDL No: MFCD00149779; RTECS: OM3756000
UN No: UN1474; Haz Class: 5.1; Packing Group: III
Crystalline; Linear Formula: Mg(NO3)2·6H2O ; MW: 256.41
Melting Point: 89° (decomposes); Boiling Point: 330°
Density (g/mL): 1.636
Hygroscopic
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