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1-Bromo-2-(cyclopropylmethoxy)benzene
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1-Bromo-2-(cyclopropylmethoxy)benzene
Supplier:
Adipogen
Description:
Zwitterionic building block for synthesis.
Supplier:
BeanTown Chemical
Description:
CAS: 32634-68-7; EC No: 251-132-2; MDL No: MFCD00008552
Powder; Molecular Formula: C20H18O8 ; MW: 386.35
Melting Point: 169-171°
Optical Rotation: [α]19/D +138°, c = 1 in ethanol
Supplier:
TCI America
Description:
CAS Number: 4519-39-5
MDL Number: MFCD00010267 Molecular Formula: C7H4F2O2 Molecular Weight: 158.10 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Melting point (°C): 164
Supplier:
Adipogen
Description:
AMG-458 is a potent inhibitor of c-Met with an IC(50) of 60nM and displays selectivity against VEGFR2.
Supplier:
Adipogen
Description:
Sensitive probe for membrane potential (Ex/Em: 555/578nm in methanol). Selective staining of immature hemopoietic cells in flow cytometry.
Supplier:
Adipogen
Description:
GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC(50) of 0.4nM, displaying at least 100-fold selectivity over the other EIF2AKs assayed.
Supplier:
TCI America
Description:
CAS Number: 38573-88-5
MDL Number: MFCD00061136 Molecular Formula: C6H3BrF2 Molecular Weight: 192.99 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Flash Point (°C): 61 Specific Gravity (20/20): 1.71
Catalog Number:
(101779-118)
Supplier:
Adipogen
Description:
GSK2126458 is an orally available selective inhibitor of the class I phosphoinositide 3-kinase (PI3K) enzymesand MTOR1/2 complexes. GSK2126458 can inhibit PI3K-alpha (p85alpha/p110alpha) with IC(50) of 0.04nM. GSK2126458 has Ki values in the picomolar range for each of the class I PI3K isoforms and MTOR1/2 complexes. GSK2126458 has potent in vitro and in vivo growth-inhibitory effects on cancer cells. In comparison with other clinical PI3K inhibitors, GSK2126458 is around 100-fold more potent than BEZ235 (6nM). GSK2126458 also a low picomolar inhibitor of the common activating mutants of p110R ( E542K, E545K, and H1047R ) with Ki of 0.008nM, 0.008nM and 0.009nM in human cancer. In mechanistic cellular assays, GSK2126458 caused a significant reduction in the levels of pAKT-S473 with remarkable potency. Consistent with its activity against both PI3K R and mTOR, GSK2126458 also inhibits phosphorylation of AKT-T308 and p70S6K at low nanomolar concentrations. GSK2126458 induces a G1 cell cycle arrest and inhibits cell proliferation in a large panel of cell lines, including T47D and BT474 breast cancer lines.
Supplier:
BeanTown Chemical
Description:
CAS: 80822-15-7; EC No: 241-097-1; MDL No: MFCD00150722
Powder; Molecular Formula: C18H14O8·H2O ; MW: 376.31
Melting Point: 150-153°
Optical Rotation: [α]20/D +109°, c = 2% in ethanol
Hygroscopic
Supplier:
BeanTown Chemical
Description:
CAS: 2743-38-6; EC No: 220-374-0; MDL No: MFCD00003074; RTECS: WW8070000
Powder; Molecular Formula: C18H14O8 ; MW: 358.30
Melting Point: 154-156°
Optical Rotation: [α]20/D −116°, c = 9 in ethanol
Supplier:
AMBEED, INC
Description:
4-Bromo-2,3-difluorophenol, Purity: 98%, CAS number: 144292-32-0, Appearance: Colorless or white to gray to brown powder or crystals , Storage: Inert atmosphere, Room Temperature, Size: 10G
Supplier:
Adipogen
Description:
N-methylated inactive control analog of 6-bromoindirubin-3'-oxime (6BIO) . Displays minimal activity against CDK1/Cyclin B, GSK-3 alpha/beta and CDK5/p25. Aryl hydrocarbon receptor (AhR) agonist; causes redistribution of AhR to the nucleus.
Supplier:
Adipogen
Description:
Antibiotic
Supplier:
Adipogen
Description:
AZD8055 is a novel ATP-competitive inhibitor of mTOR kinase activity with an IC(50) of 0.8nM. It shows excellent selectivity (~1,000-fold) against all class I phosphatidylinositol 3-kinase (PI3K) isoforms and other members of the PI3K-like kinase family.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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