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Catalog Number: (101442-562)

Supplier: Southern Biotechnology

Description: Purified Swine IgG for use as a control in flow cytometry assays and as a standard in ELISA.

Catalog Number: (100244-948)

Supplier: Southern Biotechnology

Description: Rabbit F(ab')2 Anti-Goat IgG(H+L)-HRP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.

Catalog Number: (100245-534)

Supplier: Southern Biotechnology

Description: Purified Anti-Chicken Lambda antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and immunoprecipitation assays.

Catalog Number: (100245-616)

Supplier: Southern Biotechnology

Description: In the chicken the CD8 molecule is present in two forms - (i) a homodimer of two α chains and (ii) a heterodimer of an α chain and a β chain. Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells, and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8α- and CD8β-chains, a relatively large proportion of the CD8+ TCRγδ cells in the spleens of embryos and young chicks express only the α-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCRγδ CD8αβ cells in the chicken that is not found in rodents. The monoclonal antibody 3-298 recognizes the CD8α chain of both the chicken and turkey.

Catalog Number: (100245-690)

Supplier: Southern Biotechnology

Description: PE Anti-Human IgG Fc antibody for use in flow cytometry and multiplex assays.

Catalog Number: (100244-820)

Supplier: Southern Biotechnology

Description: Porcine CD1 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It has a domain organization similar to that of MHC class I molecules and is expressed in association with β2-microglobulin. CD1 is found on B cells, macrophages, and immature thymocytes. There is evidence for a role of CD1 in presentation of lipids and peptides to T cells.

Catalog Number: (100244-878)

Supplier: Southern Biotechnology

Description: The monoclonal antibody BB6-10A10 stains the following percentages of surface immunoglobulin (sIg) positive cells in porcine lymphoid tissues - 11-15% in peripheral blood, 22-23% in mesenteric lymph nodes, 79-87% in ileal Peyer’s patches (ILPP), 6-17 in spleen, and 0% in thymus. While identification of the antigen(s) that are found predominantly on ILPP B cells and which are recognized by BB6-10A10 is speculative, the antibody appears to react with an immature population of B cells in the follicles of ILPPs and with a subpopulation of sIglow B cells in lymph nodes.

Catalog Number: (101190-224)

Supplier: Southern Biotechnology

Description: Chicken IgY-HRP for use as a control in immunocytochemistry assays.

Catalog Number: (101442-712)

Supplier: Southern Biotechnology

Description: Glial fibrillary acid protein (GFAP) is a member of the type III intermediate filament family of proteins. GFAP is heavily expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and functions of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cell; however, its precise function remains poorly understood. In adults, GFAP levels increase in response to the proliferation of astrocytes associated with Alzheimer’s disease, epilepsy, and multiple sclerosis. Antibodies specific for GFAP are useful as markers of astrocytic cells and neural stem cells as well as for distinguishing neoplasms of astrocytic origin from other neoplasms in the central nervous system.

Catalog Number: (101442-902)

Supplier: Southern Biotechnology

Description: CD11a, also known as leukocyte function-associated antigen-1 (LFA-1α), represents the 180 kDa integrin αL subunit which combines with the CD18 β2 integrin subunit to form the αLβ2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.

Catalog Number: (101442-900)

Supplier: Southern Biotechnology

Description: CD9 is a 24 kDa member of the transmembrane 4 superfamily (TM4-SF) of cell surface receptors. It is expressed strongly on platelets, lymphoid progenitor cells, activated lymphocytes and endothelia, and, weakly, on eosinophils, granulocytes, monocytes, and macrophages. CD9 functions as an adhesion molecule where it mediates platelet aggregation and activation.

Catalog Number: (100242-672)

Supplier: Southern Biotechnology

Description: Purified Goat Anti-Mouse IgG2a antibody with minimal reactivity to human proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, ELISpot, and purification assays.

Catalog Number: (100242-990)

Supplier: Southern Biotechnology

Description: Protein tyrosine residues are phosphorylated as a result of intracellular protein kinase activation (e.g., via growth factors) during normal growth and development and in oncogenesis. The most abundant population of target proteins for tyrosine phosphorylation is cell surface glycoproteins. Antibodies to phosphotyrosine enable the detection, isolation, and characterization of proteins containing phosphotyrosine. The monoclonal antibody PY20 prevents internalization of activated receptors (e.g., EGFR) when microinjected into cells. The affinity of PY20 for phosphotyrosine is approximately 10-6 to 10-7 M. PY20 binding to phosphorylated tyrosines can be inhibited by free phosphotyrosine and phenylphosphate but not by phosphoserine, phosphothreonine, or free phosphate.

Catalog Number: (100242-742)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG3-HRP antibody with minimal reactivity to human proteins for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG(H+L)-PE antibody with minimal reactivity to human proteins for use in flow cytometry assays.

Catalog Number: (100242-762)

Supplier: Southern Biotechnology

Description: Purified Goat Anti-Mouse IgE antibody for use in ELISA, flow cytometry, immunocytochemistry, western blotting, and immunoprecipitation assays.