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7-Oxoheptanoic+acid

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Description:   2-Bromo-4-(bromomethyl)benzonitrile 95%
Catalog Number: 77017-966
Supplier: AMBEED, INC



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Description:   3-Bromo-4-(bromomethyl)benzonitrile 96%
Catalog Number: 77308-262
Supplier: AMBEED, INC



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Description:   (Bromomethyl)cyclopropane, Purity: 97%, CAS Number: 7051-34-5, Appearance: Form: liquid Colour: colorless - yellow, Storage: Inert atmosphere, 2-8 C, Size: 1g
Catalog Number: 77170-940
Supplier: AMBEED, INC



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Description:   Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilize XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Catalog Number: 10319-734
Supplier: Bioss



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Description:   Methyl 2-(bromomethyl)-5-nitrobenzoate, Purity: 96%, CAS Number: 90725-68-1, Appearance: White to Yellow Solid, Storage: Inert atmosphere, 2-8 C, Size: 5g
Catalog Number: 77153-430
Supplier: AMBEED, INC



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Description:   Methyl-5-bromo-2-(bromomethyl)benzoate 95%
Catalog Number: 77036-706
Supplier: AMBEED, INC


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Description:   1-(Bromomethyl)adamantane, Purity: 98%, CAS Number: 14651-42-4, Appearance: White to Yellow Solid, Storage: Sealed in dry, Room Temperature, Size: 25g
Catalog Number: 77188-954
Supplier: AMBEED, INC



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Description:   2-Bromo-1-(bromomethyl)-3-methylbenzene 97%
Catalog Number: 77266-776
Supplier: AMBEED, INC


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Description:   Methyl 5-(bromomethyl)picolinate 96%
Catalog Number: 77879-673
Supplier: AMBEED, INC


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Description:   (Bromomethyl)cyclopentane 97%
Catalog Number: 76842-648
Supplier: AMBEED, INC



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Description:   2-(Bromomethyl)-6-fluorobenzonitrile, Purity: 97%, CAS Number: 1261686-95-6, Appearance: White to Yellow Solid, Storage: Inert atmosphere, 2-8 C, Size: 10g
Catalog Number: 77189-762
Supplier: AMBEED, INC



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Description:   Methyl 4-(bromomethyl)-3-fluorobenzoate 95%
Catalog Number: 77087-190
Supplier: AMBEED, INC



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Description:   1-(Bromomethyl)propyl ethyl ether
Catalog Number: 102665-388
Supplier: Matrix Scientific



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Description:   5-(Bromomethyl)furan-2-carbonitrile 95+%
Catalog Number: 76878-578
Supplier: AMBEED, INC



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Description:   2-Bromomethyl-6-methylpyridine 97%
Catalog Number: 77087-510
Supplier: AMBEED, INC



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Description:   4-Bromo-1-(bromomethyl)-2-nitrobenzene 98%
Catalog Number: 77306-082
Supplier: AMBEED, INC



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