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Supplier:
BeanTown Chemical
Description:
CAS: 16029-98-4; EC No: 240-171-0; MDL No: MFCD00001028
UN No: UN2924; Haz Class: 3(8); Packing Group: II
Liquid; Linear Formula: (CH3)3SiI; Molecular Formula: C3H9ISi; MW: 200.09
Boiling Point: 106°; Flash point: -2°C (28°F)
Density (g/mL): 1.406; Refractive Index: 1.471
Light Sensitive, Moisture Sensitive
Catalog Number:
(10465-408)
Supplier:
Bioss
Description:
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008].
Supplier:
BeanTown Chemical
Description:
CAS: 71-43-2; EC No: 200-753-7; MDL No: MFCD00003009; RTECS: CY1400000
UN No: UN1114; Haz Class: 3; Packing Group: II
Liquid; Molecular Formula: C6H6; MW: 78.11
Melting Point: 5.5°; Boiling Point: 80°; Flash point: -11°C (12°F)
Density (g/mL): 0.874; Refractive Index: 1.501
Supplier:
BeanTown Chemical
Description:
CAS: 13154-24-0; MDL No: MFCD00009656
UN No: UN2987; Haz Class: 8; Packing Group: II
Liquid; Linear Formula: [(CH3)2CH]3SiCl; Molecular Formula: C9H21ClSi; MW: 192.81
Boiling Point: 198°/739 mmHg; Flash point: 64°C (147°F)
Density (g/mL): 0.901; Refractive Index: 1.452
Moisture Sensitive
Catalog Number:
(77439-300)
Supplier:
Bioss
Description:
Angiotensinogen protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia.
Supplier:
BeanTown Chemical
Description:
CAS: 592-13-2; EC No: 209-745-8; MDL No: MFCD00008951
UN No: UN3295; Haz Class: 3; Packing Group: II
Liquid; Linear Formula: (CH3)2CHCH2CH2CH(CH3)2; Molecular Formula: C8H18; MW: 114.23
Boiling Point: 108°; Flash point: 26°C (79°F)
Density (g/mL): 0.694; Refractive Index: 1.392
Supplier:
BeanTown Chemical
Description:
CAS: 865-48-5; EC No: 212-741-9; MDL No: MFCD00040575
UN No: UN3206; Haz Class: 4.2 (8); Packing Group: II
Powder; Linear Formula: NaOC(CH3)3; Molecular Formula: C4H9NaO; MW: 96.11
Melting Point: 300° (decomposes); Flash point: 14°C (57°F)
Density (g/mL): 0.785
Air Sensitive, Moisture Sensitive
Catalog Number:
(10280-070)
Supplier:
Bioss
Description:
Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1–6). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).
Catalog Number:
(10482-218)
Supplier:
Bioss
Description:
Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
Catalog Number:
(10750-934)
Supplier:
Prosci
Description:
PIAS1 Antibody: The PIAS proteins (protein inhibitor of activated STAT) play a crucial role as transcriptional coregulators in various cellular pathways, including the STAT, p53 and the steroid hormone signaling pathway. The PIAS protein family includes at least five evolutionarily conserved genes, including PIAS1. The major function of the PIAS proteins is the control of gene transcription and can also act as small ubiquitin-like-modifier (SUMO) E3 ligases. PIAS1 binds specifically to STAT1, inhibiting STAT1-mediated gene activation and also binds to the Gu/RNA helicase II enzyme, leading to the proteolytic cleavage of Gu/RH-II. PIAS1 is a potent co-activator for CP2c-mediated alpha-globin expression in erythroid cells.
Catalog Number:
(75793-030)
Supplier:
Prosci
Description:
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Catalog Number:
(75844-318)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The HIT2 monoclonal antibody specifically bind to human CD38, a 45kda type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, macrophages, dendritic cells, and thymocytes. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.
Catalog Number:
(75844-322)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The HIT2 monoclonal antibody specifically bind to human CD38, a 45kda type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, macrophages, dendritic cells, and thymocytes. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.
Supplier:
BeanTown Chemical
Description:
CAS: 7101-31-7; EC No: 230-410-7; MDL No: MFCD00008254
UN No: UN2929; Haz Class: 6.1 (3); Packing Group: II
Liquid; Linear Formula: (CH3)2Se2 ; MW: 187.99
Boiling Point: 155-157°; Flash point: 60°C (140°F)
Density (g/mL): 1.987 ; Refractive Index: 1.639
Air Sensitive, Moisture Sensitive
Supplier:
BeanTown Chemical
Description:
CAS: 7803-57-8; EC No: 206-114-9; MDL No: MFCD00149931; RTECS: MV4590000
UN No: UN2030; Haz Class: 8 (6.1); Packing Group: II
Liquid; Linear Formula: H2NNH2·H2O; MW: 50.06
Melting Point: -52°; Boiling Point: 120.1°; Flash point: 75°C (167°F)
Density (g/mL): 1.032; Refractive Index: 1.428
Supplier:
BeanTown Chemical
Description:
CAS: 106-89-8; EC No: 203-439-8; MDL No: MFCD00005132; RTECS: TX4900000
UN No: UN2023; Haz Class: 6.1 (3); Packing Group: II
Liquid; Molecular Formula: C3H5ClO; MW: 92.53
Boiling Point: 114-117°; Flash point: 32°C (90°F)
Density (g/mL): 1.182; Refractive Index: 1.438
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is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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