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N,N-Dimethylformamide dimethyl acetal
Supplier:
Enzo Life Sciences
Description:
Potent antitumor agent
Supplier:
TCI America
Description:
CAS Number: 7689-03-4
MDL Number: MFCD00081076 Molecular Formula: C20H16N2O4 Molecular Weight: 348.36 Purity/Analysis Method: >97.0% (HPLC) Form: Crystal Specific rotation [a]20/D: 40 deg (C=0.4, CHCl3:MeOH=8:2)
Supplier:
MP Biomedicals
Description:
(S)-(+)-Camptothecin binds irreversibly to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA.
Catalog Number:
(80055-998)
Supplier:
AMBEED, INC
Description:
(S)-(+)-Camptothecin ≥98%
Supplier:
Thermo Scientific Chemicals
Description:
Cytotoxic antitumor agent that inhibits topoisomerase I
Supplier:
APOLLO SCIENTIFIC
Description:
(S)-(+)-Camptothecin
Catalog Number:
(82021-598)
Supplier:
G-Biosciences
Description:
Apoptosis is commonly defined as programmed mechanism of cell death and is a highly regulated process that can be initiated by a variety of internal and external stimuli (inducers).
Supplier:
Adipogen
Description:
Potent anticancer compound. Cell permeable potent DNA topoisomerase I (Topo I) complex inhibitor. Potent apoptosis inducer. Binds reversibly to the DNA topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. The enzyme complex is ubiquinated and destroyed by the 26S proteasome, consequently depleting cellular topoisomerase I. Prevents DNA re-ligation and therefore causes DNA damage which results in apoptosis. Inhibits mitochondrial topoisomerase I (mtTop1). Blocks the cell cycle at low dose and induces apoptosis in a large number of normal and tumor cell lines by cell cycle-dependent and cell cycle-independent processes. Antiprotozoal and antimalarial compound. Inhibitor of HIV replication and of other viruses. Suppresses nitric oxide (NO) biosynthesis. Shown to suppress TNF-alpha-induced expression of the inflammasome and cyclooxygenase 2 (COX-2).
Supplier:
Matrix Scientific
Description:
MF=C20H16N2O4 MW=348.36 CAS=7689-03-4 MDL=MFCD00081076 5G
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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