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Proteins and Peptides
Catalog Number:
(89160-340)
Supplier:
Enzo Life Sciences
Description:
The deacetylated state of lysine-16 of histone H4 (H4-K16) is thought to be a critical factor in determining regions of chromatin silencing. Conversely, acetylation of lysine-16 can be associated with increased transcription, such as that due to dosage compensation from the X-chromosome of male Drosophila. The acetylated H4 lysine-16 is preferentially deacetylated by yeast Sir2 in vitro and in vivo. Fluor de Lys®-H4-AcK16 is a fluorogenic, acetylated peptide substrate suitable for various lysine deacetylases, including the HDAC activities in HeLa nuclear extract, HDAC8, SIRT1 (human Sirtuin 1) and SIRT2 (human Sirtuin 2). It is based on residues from histone H4 (12-16, Lys-Gly-Gly-Ala-Lys(Ac)) and was the preferred substrate for both SIRT1 and SIRT2 within a group patterned on acetylation sites in histone H3 and histone H4 N-terminal tails. Fluor de Lys®-H4-AcK16 is deacetylated by SIRT1 (BML-SE239) at a rate of more than 6-fold and by SIRT2 (BML-SE251) at a rate of more than 40-fold those achieved with the acetylated lysine substrate, Fluor de Lys® (BML-KI104; acetylated substrates both at 25 µM, 500 µM NAD ). Must be used in conjunction with Fluor de Lys® Developer (BML-KI104). Sufficient for 100-200 assays (50-100 µM substrate).
Catalog Number:
(75935-206)
Supplier:
Rockland Immunochemical
Description:
Rb control protein-GST fusion
Catalog Number:
(89161-580)
Supplier:
Enzo Life Sciences
Description:
Calpain and cathepsin inhibitor
Catalog Number:
(75930-692)
Supplier:
Rockland Immunochemical
Description:
p33ING1 control protein-HIS Epitope
Catalog Number:
(89146-770)
Supplier:
Enzo Life Sciences
Description:
Caspase-3 substrate
Supplier:
Rockland Immunochemical
Description:
Recombinant Rat CCL2 control protein
Catalog Number:
(89161-034)
Supplier:
Enzo Life Sciences
Description:
ACE substrate
Catalog Number:
(75931-380)
Supplier:
Rockland Immunochemical
Description:
PTK9 control protein-GST fusion
Catalog Number:
(89145-042)
Supplier:
Enzo Life Sciences
Description:
Produced in HEK 293 cells. The collagen domain of mouse ACRP30 (aa 18-111) is fused at the N-terminus to a linker peptide (8 aa) and a FLAG®-tag.
Catalog Number:
(76003-326)
Supplier:
Enzo Life Sciences
Description:
Produced in E. coli.
Catalog Number:
(RL009-0033)
Supplier:
Rockland Immunochemical
Description:
1mg. Antibody Concentration: 1 mg/mL. Fluorochrome/Protein: 2.7 moles TRITC per mole of Human Albumin. Buffer: 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2. Stabilizer: 10 mg/mL BSA IgG and protease free. For research. Lyophilized.
Catalog Number:
(89161-116)
Supplier:
Enzo Life Sciences
Description:
AMPK substrate
Catalog Number:
(89164-214)
Supplier:
Enzo Life Sciences
Description:
Produced in Sf9 cells. Human VEGFR2 (aa 805-1356).
Catalog Number:
(75932-092)
Supplier:
Rockland Immunochemical
Description:
SOD2 control protein-GST fusion
Catalog Number:
(89161-280)
Supplier:
Enzo Life Sciences
Description:
Inhibits NF-kappaB translocation
Supplier:
Enzo Life Sciences
Description:
Caspase and granzyme substrate
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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