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Catalog Number:
(102551-444)
Supplier:
Matrix Scientific
Description:
2'-IODOACETOPHENONE MF=C8H7IO MW=246.05 CAS=2142-70-3 MDL=MFCD00094998
Catalog Number:
(101787-866)
Supplier:
Matrix Scientific
Description:
MF=C7H7Is MW=250.10 Cas=33775-94-9 MDL=MFCD00051611 25G
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
4'-Iodoacetophenone 98%
Catalog Number:
(76012-366)
Supplier:
Prosci
Description:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq].
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
4'-Iodoacetanilide 97%
Supplier:
AOB CHEM USA
Description:
1,3-Difluoro-4-iodo-2-methylsulfanylbenzene ≥97%
Supplier:
Matrix Scientific
Description:
MF=C11H15I MW=274.15 Cas=85017-60-3 MDL=MFCD00079767 1G
Supplier:
AMBEED, INC
Description:
(S)-N-(3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide, Purity: 98+%, CAS Number: 923032-37-5, Appearance: Pale-yellow to Yellow-brown Solid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 50mg
Supplier:
APOLLO SCIENTIFIC
Description:
3-Iodobenzyl alcohol, Technical Grade
Supplier:
Matrix Scientific
Description:
MF=C8H7Io MW=246.05 Cas=14452-30-3 MDL=MFCD00060283 25G
Supplier:
AMBEED, INC
Description:
4-Iodobenzylamine hydrochloride 97%
Catalog Number:
(10304-184)
Supplier:
Bioss
Description:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
Supplier:
AOB CHEM USA
Description:
2-Bromo-6-iodoanisole ≥95%
Supplier:
AMBEED, INC
Description:
AS-703026 98%, Ambeed.Inc
Supplier:
AMBEED, INC
Description:
N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide dimethyl sulfoxide complex 98%
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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