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Supplier:
Enzo Life Sciences
Description:
Potent antitumor agent
Supplier:
TCI America
Description:
CAS Number: 7689-03-4
MDL Number: MFCD00081076 Molecular Formula: C20H16N2O4 Molecular Weight: 348.36 Purity/Analysis Method: >97.0% (HPLC) Form: Crystal Specific rotation [a]20/D: 40 deg (C=0.4, CHCl3:MeOH=8:2)
Supplier:
MP Biomedicals
Description:
(S)-(+)-Camptothecin binds irreversibly to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA.
Catalog Number:
(80055-998)
Supplier:
AMBEED, INC
Description:
(S)-(+)-Camptothecin ≥98%
Supplier:
Thermo Scientific Chemicals
Description:
Cytotoxic antitumor agent that inhibits topoisomerase I
Supplier:
APOLLO SCIENTIFIC
Description:
(S)-(+)-Camptothecin
Catalog Number:
(82021-598)
Supplier:
G-Biosciences
Description:
Apoptosis is commonly defined as programmed mechanism of cell death and is a highly regulated process that can be initiated by a variety of internal and external stimuli (inducers).
Supplier:
Adipogen
Description:
Potent anticancer compound. Cell permeable potent DNA topoisomerase I (Topo I) complex inhibitor. Potent apoptosis inducer. Binds reversibly to the DNA topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. The enzyme complex is ubiquinated and destroyed by the 26S proteasome, consequently depleting cellular topoisomerase I. Prevents DNA re-ligation and therefore causes DNA damage which results in apoptosis. Inhibits mitochondrial topoisomerase I (mtTop1). Blocks the cell cycle at low dose and induces apoptosis in a large number of normal and tumor cell lines by cell cycle-dependent and cell cycle-independent processes. Antiprotozoal and antimalarial compound. Inhibitor of HIV replication and of other viruses. Suppresses nitric oxide (NO) biosynthesis. Shown to suppress TNF-alpha-induced expression of the inflammasome and cyclooxygenase 2 (COX-2).
Supplier:
Matrix Scientific
Description:
MF=C20H16N2O4 MW=348.36 CAS=7689-03-4 MDL=MFCD00081076 5G
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is still displayed and you need assistance, please call us at 1-800-932-5000.
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