400-051-G001
400-051-G005
89150-668EA
50.14
USD
InStock
89150-668
89150-670
Cyclophosphamide monohydrate (synthetic) ≥97% (by HPLC)
Cyclophosphamide monohydrate
Alkylates DNA, forming DNA-DNA cross-links that result in inhibition of DNA synthesis and cell death
- DNA alkylating agent
- Source: synthetic
- Appearance: White to off-white crystalline solid
- Soluble in water; slightly soluble in 100% ethanol
Interestingly the repair enzyme O6-alkylguanine-DNA alkyltransferase, long thought to be involved with resistance to methylating and chloroethylating agents, may also contribute to resistance to the cytotoxic and mutagenic effects of cyclophosphamide.