430-041-G001
430-041-M300
89150-954EA
280.13
USD
InStock
89150-954
89150-956
Protoporphyrin IX ≥95% (by HPLC)
Protoporphyrin IX
Protoporphyrin IX free acid, as distinct from its zinc salt (which inhibits heme oxygenase), activates soluble guanylyl cyclase (sGC) by binding directly to the enzyme. A useful reagent in cases where the use of nitric oxide (NO) or nitric oxide donors is undesirable.
- Guanylyl cyclase activator
Purple to dark brown solid.
Dissolve initially in 0.1M base (Tris base or NaOH), then add water miscible organic solvent (EtOH (10mg/ml), MeOH, DMSO (10mg/ml), DMF) until solution is 50/50 base/solvent. When a clear solution is obtained, it can be diluted into an aqueous medium and titrated or buffered to any pH>7. Use immediately.