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HA14-1 ≥95%

Supplier: SAFE AND SURE NEDERLAND B.V.
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430-101-M005 430-101-M025
89151-112EA 78.48 USD InStock
89151-112 89151-114
HA14-1 ≥95%
HA14-1
Bcl-2 ligand.

  • Formulation: Off-white to light yellow powder.

Cell permeable, low molecular weight Bcl-2 ligand. Antagonizes the function of Bcl-2 and induces apoptosis. In HL-60 cells, HA4-1 (50µM and 4h incubation) induced apoptosis of more than 90% of the cells. Apoptosis is blocked by ZVAD-FM. IC50 = ~9µM for competition with Flu-BakBH3 binding to Bcl-2.

Soluble in DMSO (25 mg/mL, dimethyl formamide or halogenated solvents; also soluble in 100% ethanol (25 mg, 7 mL hot).


Formula: C₁₇H₁₇BrN₂O₅
MW: 409.24 g/mol
Storage Temperature: Freezer
 MDL Number: MFCD00218213
CAS Number: 65673-63-4
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Specification Test Results
Purity (¹H-NMR) ≥95%
Identity Identity determined by IR, ¹H-NMR
Appearance Off-white to light yellow powder

 

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