550-516-M005
550-516-M025
89152-722EA
73.03
USD
InStock
89152-722
89152-724
Compound A ≥98% (by HPLC)
Compound A
Glucocorticoid receptor modulator.
- Formulation: White to off-white solid.
Cell permeable, nonsteroidal glucocorticoid receptor modulator with high binding affinity.
Exerts anti-inflammatory potential by down-modulating TNF-induced pro-inflammatory gene expression, such as IL-6 and E-selectin. Unlike dexamethasone it does not enhance glucocorticoid response element (GRE)-driven gene expression or induce glucocorticoid receptor (GR) binding to GRE-dependent genes in vivo.
Soluble in DMSO, 100% ethanol or water.
Synonym: CpdA; 2-((4-acetophenyl)-2-chloro-N-methyl)ethylammonium chloride