BML-CN210-0020
BML-CN210-0100
89157-036EA
99.19
USD
InStock
89157-036
89157-038
(±)-S-Nitroso-N-acetylpenicillamine (SNAP) ≥98% (by TLC)
(±)-S-Nitroso-N-acetylpenicillamine (SNAP)
Stable analog of endogenous S-nitroso compounds. Nitric oxide (NO) donor and a source of NO in vivo which spontaneously releases NO under physiological conditions. The half-life time is 4.6 hours in aqueous media.
- Releases NO under physiological conditions
- Green crystalline solid
Potent vasodilator in vitro and in vivo that does not induce pharmacological tolerance. Relaxes isolated bovine coronary artery rings with an EC50=0.1µM. It also inhibits vascular smooth muscle cell mitogenesis and proliferation, inhibits leukocyte adherence to endothelium, and inhibits cysteine proteases. The unique NO releasing properties of SNAP make it an ideal agent for studying the pharmacological and physiological actions of NO.
Soluble in DMSO (25mg/ml) 100% ethanol (25mg/ml) or methanol; slightly soluble in water (2mg/ml).