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Dorsomorphin ≥98% (by TLC)

Supplier: SAFE AND SURE NEDERLAND B.V.
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BML-EI369-0005 BML-EI369-0025
89158-206EA 124.26 USD InStock
89158-206 89158-208
Dorsomorphin ≥98% (by TLC)
Dorsomorphin
Cell-permeable pyrrazolopyrimidine derivative that inhibits AMP kinase (Ki=109nM in the absence of AMP) in an ATP-competitive manner. It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. Decreases food intake in mice and inhibits the effects of AICAR and metformin. It has been shown to inhibit BMP type I receptors ALK2, ALK3 and ALK6. Promotes cardiomyogenesis in mouse embryonic stem cells. Induces protective autophagy in cancer cell lines.

  • AMPK inhibitor

Yellow solid.

Soluble in DMSO (3mg/ml, warm)


Formula: C₂₄H₂₅N₅O
MW: 399.5 g/mol
Storage Temperature: Freezer
 MDL Number: MFCD08705402
CAS Number: 866405-64-3
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