AG-CN2-0008-C500
AG-CN2-0008-M001
102515-684EA
166.15
USD
InStock
102515-684
102515-686
Hyperforin·DCHA ≥97% (by HPLC)
Hyperforin DCHA
Key constituent of St. John's wort. Shows properties of potential pharmacological interest, including antibacterial, anti-malarial, anti-inflammatory, anti-cancer and anti-angiogenic effects. Anti-depressant and anxiolytic compound. Specific activator of TRPC6 channels. Inhibits the re-uptake of neurotransmitters in synapses (serotonin, norepinephrine, dopamine, GABA, glutamate). Activator of the pregnane X receptor (PXR). Regulates expression of the cytochrome P450 CYP3A4 and CYP2C9 and hepatic drugs metabolism. Potential anti-Alzheimer compound. Potent SIRT1 (sirtuin 1) and SIRT2 (sirtuin 2) inhibitor.