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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Wortmannin (from Penicillium species) ≥98% (by HPLC)

Supplier: Van Der Voort Lucht en Milieu Amste

AG-CN2-0023-M001 AG-CN2-0023-M005 AG-CN2-0023-M025
102515-746EA 55.38 USD InStock
102515-746 102515-748 102515-750
Wortmannin (from Penicillium species) ≥98% (by HPLC)
Wortmannin
Wortmannin is a potent anti-neutrophil agent with cardioprotective effects.

  • Cell permeable and selective inhibitor
  • More suitable inhibitor than 3-MA
  • TRAIL sensitizer

Antibiotic. mTOR, DNA-PK, phosphatidylinositol 4-kinases, myosin light chain kinase (MLCK) and mitogen-activated protein kinase (MAPK) inhibitor at high concentrations. Potent cell permeable and selective inhibitor of phosphatidyl-inositol 3-kinase (PI3K). Similar potency in vitro for the class I, II, and III PI3K. Antitumor compound. Radiosensitizing agent. Adipogenesis inhibitor. Angiogenesis inhibitor. Autophagy inhibitor, regardless of the nutrient status and thus is a more suitable autophagy inhibitor than 3-MA. DNA repair, receptor-mediated endocytosis and cell proliferation inhibitor. Potentiates the LPS-induced nitric oxide (NO) production from macrophages. Induces in vivo Alzheimer-like hyperphosphorylation in tau. Polo-like kinase family inhibitor.

White to off-white solid

Stable for at least 2 years after receipt when stored at -20°C.

Soluble in DMSO methanol, ethanol or chloroform. Slightly soluble in water.


Formula: C₂₃H₂₄O₈
Storage Temperature: Freezer
 MDL Number: MFCD00133927
CAS Number: 19545-26-7
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