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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Rapamycin (from Streptomyces hygroscopicus) ≥98%

Supplier: Van Der Voort Lucht en Milieu Amste

AG-CN2-0025-C100 AG-CN2-0025-M001 AG-CN2-0025-M005 AG-CN2-0025-M025
102515-756EA 34.62 USD InStock
102515-756 102515-758 102515-760 102515-762
Rapamycin (from Streptomyces hygroscopicus) ≥98%
Rapamycin
Rapamycin, isolated from Streptomyces hygroscopicus, forms a complex with FKBP12 and inhibits the molecular target of rapamycin (mTOR). It blocks the activation of T and B cells.

  • Blocks activation of T and B cells
  • Antibiotic. Antibacterial and antifungal properties
  • Potent immunosuppressant used as an alternative to calcineurin inhibitors
  • Cell cycle progression (at the G1/S transition) inhibitor
  • Antiproliferative, antitumor compound, anti-HIV and anti-aging compound
  • Apoptosis enhancer and activator of autophagy
  • Purity: ≥98%

Forms a complex with FKBP12 and inhibits the mammalian target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an alternative to calcineurin inhibitors. Restricts the proliferation of smooth-muscle cells by blocking cell cycle progression at the G1/S transition. Anti-proliferative. Antitumor compound. Activator of autophagy both in vitro and in vivo. Anti-HIV and anti-aging compound. Neuroprotective. Suppressor for self-renewal and vascular differentiation potential in hemangioma stem cells. Stability: Soluble in DMSO, methanol or chloroform. Stable for at least 2 years after receipt when stored at long term storage −20 °C. Short term storage at 4 °C.

White to off-white solid

Stable for at least two years after receipt when stored at -20°C.

Soluble in DMSO, methanol or chloroform.


Formula: C₅₁H₇₉NO₁₃
MW: 914.19 g/mol
Storage Temperature: Freezer
 MDL Number: MFCD00867594
CAS Number: 53123-88-9
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