AG-CR1-0029-M001
AG-CR1-0029-M005
102515-984EA
27.69
USD
InStock
102515-984
102515-986
PD 184,352 ≥95%
PD 184,352
MEK (MAPKK) inhibitor. Potent and selective MAPK (ERK kinase 1; MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo). Suppresses activation of MAPK but does not block its activity. Antiproliferative. Causes cell-cycle arrest in G1 phase. Tumor suppressor. Apoptosis inducer.