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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Bisindolylmaleimide I hydrochloride ≥98%

Supplier: Van Der Voort Lucht en Milieu Amste

AG-CR1-0110-M001 AG-CR1-0110-M005
102516-154EA 76.15 USD InStock
102516-154 102516-156
Bisindolylmaleimide I hydrochloride ≥98%
Bisindolylmaleimide I hydrochloride
Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM). Competitive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Necrosis inhibitor. Blocks hERG potassium channels. Promotes osteoblastogenesis in human mesenchymal stem cells.


Formula: C₂₅H₂₄N₄O₂·HCl
Storage Temperature: Freezer
 CAS Number: 176504-36-2
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Specification Test Results
Purity 98% (NMR)
Appearance/Color Orange to red powder.
Solubility Soluble in DMSO or methanol. Slightly soluble in water.

 

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