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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Demecolcine ≥98%

Supplier: Van Der Voort Lucht en Milieu Amste
Danger

AG-CR1-3567-M001 AG-CR1-3567-M005
102516-304EA 41.54 USD InStock
102516-304 102516-306
Demecolcine ≥98%
Demecolcine
Anti-cancer compound. Cell synchronization agent. Used as a drug in chemotherapy by synchronizing tumor cells at metaphase, the radiosensitive stage of the cell cycle. Microtubule assembly inhibitor. Depolymerizes microtubules and limits microtubule formation (inactivates spindle fibre formation). Inhibits mitosis during cell division at metaphase by inhibiting spindle formation. Low concentrations affect microtubule dynamics and cell migration, while high concentrations promote microtubule detachment from microtubule organizing center. Apoptosis inducer. Thrombopoietic agent.


Formula: C₂₁H₂₅NO₅
MW: 371.433 g/mol
Storage Temperature: Freezer
 MDL Number: MFCD00075459
CAS Number: 477-30-5
UN: 2811
ADR: 6.1 III
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Specification Test Results
Source/Host Semisynthetic from colchicine (Prod. No. AG-CN2-0048).
Purity 98% (HPLC)
Appearance/Color White to off-white powder.
Solubility Soluble in ethanol, DMSO or chloroform.

 

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