BVT-0196-C100
BVT-0196-C500
BVT-0196-M001
BVT-0196-M005
102513-592EA
27.69
USD
InStock
102513-592
102513-594
102513-596
102513-598
Geldanamycin (from Streptomyces hygroscopicus) ≥98% (by HPLC)
Geldanamycin
Geldanamycin is a potent nuclear hormone receptor family inhibitor.
- Antibiotic
- Inhibits c-mycgene expression in murine lymphoblastoma cells
- Potent antitumor compound
Antibiotic. pp60src tyrosine kinase inhibitor. Inhibits the transforming activity of abl, erbB, fps, src and yes. Binds specifically to heat shock protein 90 (HSP90) and to its endoplasmic reticulum homolog GP96 (GRP94). Destabilizes several oncogene and proto-oncogene products.
Solid
After reconstitution protect from light at -20°C. Stable for at least one year after receipt when stored at -20°C.
Colour: Yellow