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Spermine tetrahydrochloride 96, powder_white

Supplier: E. Becker & Co. GmbH
Warning

0210047401 0210047410 0210047405
IC10047401EA 90.11 USD InStock
IC10047401 IC10047410 IC0210047405
Spermine tetrahydrochloride 96, powder_white
Spermine tetrahydrochloride
Spermine is a naturally occuring polyamine that occurs in all eukaryotes, but is rare in prokaryotes. It is essential for cell growth in both normal and neoplastic tissue.

Spermine is formed through the addition of an aminopropyl group to spermidine by spermine synthase. Spermine is strongly basic in character, and in aqueous solution at physiological pH, all of its amino groups will be positively charged.

Used to precipitate DNA from low salt aqueous buffers. Spermine tetrahydrochloride was used to precipitate DNA for flow cytometric analysis from fresh frozen breast cancer tissue, archival tissue of salivary gland, renal and thyroid tumors and red blood cells of chicken.

Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site.

Soluble in water (100 mg/mL - clear, colorless solution).

Spermine is a naturally occuring polyamine that occurs in all eukaryotes, but is rare in prokaryotes. It is essential for cell growth in both normal and neoplastic tissue. Spermine is formed through the addition of a aminopropyl group to spermidine by spermine synthase. Spermine is strongly basic in character, and in aqueous solution at physiological pH, all of its amino groups will be positively charged.

Precaución: Research Use Only (RUO).


Formula: C₁₀H₃₀Cl₄N₄
MW: 348.19 g/mol
Melting Pt: 312…314 °C (lit.)
Storage Temperature: Freezer
 MDL Number: MFCD00012914
CAS Number: 306-67-2
https://qa.digitalassets.avantorsciences.com/adaptivemedia/rendition?id=13ab95f8c6b1712effac22f99f2eaaf655dc8ddd&vid=13ab95f8c6b1712effac22f99f2eaaf655dc8ddd&prid=web&clid=SAPDAM https://qa.digitalassets.avantorsciences.com/adaptivemedia/rendition?id=c85df93886d76b307feff1c1878574e0f8b01db5&vid=c85df93886d76b307feff1c1878574e0f8b01db5&prid=web&clid=SAPDAM
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Specification Test Results
Identity Test Passes
Purity ≥96%
FTIR Conforms to Standard

 

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