0210049802
0210049810
0210049820
IC10049802EA
194.45
USD
InStock
IC10049802
IC10049810
IC10049820
Mitomycin C
Mitomycin C
Mitomycin C is the most widely used antibiotics because it is the least toxic and with the most potent antitumor activity.
- pH: 6 - 9
- Physical form: Blue powder
- Contains 2 mg/vial of pure mitomycin C
Inhibitor of DNA synthesis, nuclear division, and cancer cells
Synonyms: Ametycin, 7-Amino-9-a-methoxymitosane, Mit-C, Mitocin-C, Mitomycinum, Mutamycin, Azirizino[2', 3': 3,4] pyrrolo [1,2-a] indole 4,7-dione-6-amino-1,1a, 2, 8, 8a, 8b-hexahydro- 8- (hydroxymethyl) 8a-methoxy-5-methyl carbamate.
Antibacterial to gram positive, gram negative, acid-fast bacilli. Mitomycin C decomposes DNA in cancer cells by forming a complex with DNA and inhibits division of cancer cells by interfering with the biosynthesis of DNA.
Extinktion coefficients: EmM (367 nm) = 21.84 (water); EmM (357 nm) = 22.78 (methanol); E1% (216 nm) = 742 (methanol); E1% (360 nm) = 742 (methanol); E1% (560 nm) = 0.06 (methanol)(Lit.)
Soluble in dilute aqueous acids or dilute aqueous bases