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Glycine 98, powder

Supplier: E. Becker & Co. GmbH

02100570.5 0210057001 0210057005 0210057025
IC100570.5EA 57.75 USD InStock
IC100570.5 IC10057001 IC10057005 IC10057025
Glycine 98, powder
Glycine
Glycine is a non-essential amino acid. Acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. Shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. Also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons. It does not have a chiral center, so only amino acid with no asymmetric carbon. Therefore, it does not have a D- or L- isomer designation. This material is synthetic. It is the smallest of the 20 natural amino acids.

Glycine is commonly used as a component in Tris-glycine and Tris-glycine-SDS running buffers for polyacrylamide gel electrophoresis, a component of Towbin's transfer buffer for Western blots, a buffer substance in cryoenzymology, in osmotic pressure maintenance in isoelectric focusing of erythrocytes, salting-in effect in protein chemistry, and as a buffer component in the coupled phosphatase-kinase reaction for end labelling of restriction fragments. The growth requirements of various microorganisms is reported in the Handbook of Microbiology.

It is a non-chiral amino acid that can be synthesised in the body from the amino acid serine by Serine Hydroxy methyltransferase.

Soluble in water (250 mg/mL at 25 °C; 672 mg/mL at 100 °C); slightly soluble in alcohol and ethanol(95%); almost insoluble in ether.

Glycine is a non-essential amino acid. Acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. Shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. Also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons. Glycine does not have a chiral center, so only amino acid with no asymmetric carbon. Therefore, it does not have a D- or L- isomer designation. This material is synthetic.It is the smallest of the 20 natural amino acids.


Formula: NH₂CH₂COOH
MW: 75.07 g/mol
Boiling Pt: 181
Melting Pt: 83
 MDL Number: MFCD00008131
CAS Number: 56-40-6
Merck Index: 13,04504
https://qa.digitalassets.avantorsciences.com/adaptivemedia/rendition?id=629a715d6b9ac1ea9916868ff36707eae159ca51&vid=629a715d6b9ac1ea9916868ff36707eae159ca51&prid=web&clid=SAPDAM
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Specification Test Results
Synonyms Aminoacetic acid; Gly; Aminoethanoic acid; Glycocoll
Form Powder
Storage Store at Room Temperature (15-30 °C).
Isoelectric Point 6.06
Loss on Drying ≤0.5%
pka for the α carboxyl group: 2.35; and for the α amino group: 9.78 at 25 °C

 

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