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Menadione (2-methyl-1,4-naphthoquinone, vitamin K3) ≥98%, yellow powder

Supplier: E. Becker & Co. GmbH
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0210225925 0210225980
IC10225925EA 83.35 USD InStock
IC10225925 IC10225980
Menadione (2-methyl-1,4-naphthoquinone, vitamin K3) ≥98%, yellow powder
Menadione (2-methyl-1,4-naphthoquinone, vitamin K3)
Menadione belongs to the Vitamin K class of compounds, which are necessary for the biosynthesis of prothrombin and other blood clotting factors. Menadione has demonstrated cytotoxic activity against a variety of cell culture lines and can induce apoptosis of cultured cells, such as osteoclasts and osteoblasts, via elevation of peroxide and superoxide radical levels.

It is a prothrombogenic compound1 and is used as a model quinone in cell culture and in vivo investigations.

Menadione (Vitamin K3) is a synthetic analogue of of 1,4-naphthoquinone with a methyl group in the 2-position. It is used as a phosphatase inhibitor and an inhibitor of mitochondrial DNA polymerase γ (pol γ). It can be used as an oxidative injury (free radical generator) inducing agent.

Soluble in methanol (15 mg/ml-clear solution).

Menadione belongs to the Vitamin K class of compounds, which are necessary for the biosynthesis of prothrombin and other blood clotting factors. Menadione has demonstrated cytotoxic activity against a variety of cell culture lines and can induce apoptosis of cultured cells, such as osteoclasts and osteoblasts, via elevation of peroxide and superoxide radical levels.


Formula: C₁₁H₈O₂
Storage Temperature: Ambient
 MDL Number: MFCD00001681
CAS Number: 58-27-5
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Specification Test Results
Identity Test Passes
Purity ≥98%
FTIR Conforms to Standard
Melting Point 100 - 110°C
Expiration Date Month/Day/Year

 

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