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Tetracycline (from Streptomyces species), yellow powder

Supplier: E. Becker & Co. GmbH

0210301205 0210301225 0210301280
IC10301205EA 57.31 USD InStock
IC10301205 IC10301225 IC10301280
Tetracycline (from Streptomyces species), yellow powder
Tetracycline
Tetracyline is an antibiotic substance (gram-positive, gram-negative and mycoplasma) produced by Streptomyces spp.

Tetracyline inhibits gram-positive, gram-negative and mycoplasma. It is used in tetracycline controlled gene expression systems (gene switches) such as the tet-on and tet-off systems. It is also used to select tetracyline resistant colonies in cell culture.

Tetracycline binds to the 30S subunit of the ribosome at the A-site. During protein biosynthesis, the new t-RNA with the amino acid attempts to bind to the A-site of the ribosome. However, since the A-site is blocked by the tetracycline, the aminoacyl-tRNA cannot bind to it. Without the attachment of the tRNA, protein biosynthesis cannot occur. Protein biosynthesis is inhibited and cell death occurs .

Soluble in water (1.7 mg/mL), or methanol (> 20 mg/mL - clear, yellow solution).

Tetracyline is an antibiotic substance (gram-positive, gram-negative and mycoplasma) produced by Streptomyces spp.

Precaución: Research Use Only (RUO).


Formula: C₂₂H₂₄N₂O₈
MW: 444.43 g/mol
Storage Temperature: Freezer
 MDL Number: MFCD00151232
CAS Number: 60-54-8
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Specification Test Results
Identity Test Passes
Potency ≥900 μg/mg
FTIR Conforms to Standard
UV/VIS: max (0.1N HCl) 215 - 220, 266 - 271, 354 - 357 nm
Expiration Dat Month/Day/Yea

 

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