0215187605
0215187610
IC15187605EA
140.84
USD
InStock
IC15187605
IC15187610
Fosfomycin disodium salt
Fosfomycin disodium salt
Phosphomycin, also known as Fosfomycin, is an antibiotic produced by Streptomyces fradiae. Phosphomycin concentrates in kidney and bladder, reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents.
Phosphomycin disodium salt is used to treat uncomplicated urinary tract infections and to reduce nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents
Phosphomycin is a phosphoenolpyruvate analog that irreversibly inhibits UDP-GlcNAc enolpyruvyl tranferase (MurA), an enzyme involved in bacterial cell wall biosynthesis. As a result, the production of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall, is inhibited.
It is used for susceptibility studies of Klebsiella pneumoniae and to study in vitro susceptibility testing procedures for fosfomycin tromethamine.
Soluble in water (50 mg/mL- clear, colorless solution) and 1 M HCl (50 mg/mL)