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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Spectinomycin dihydrochloride pentahydrate

Supplier: E. Becker & Co. GmbH

0215206701 0215206705 0215206725
IC15206701EA 55.12 USD InStock
IC15206701 IC15206705 IC15206725
Spectinomycin dihydrochloride pentahydrate
Spectinomycin dihydrochloride pentahydrate
Spectinomycin is an aminocyclitol antibiotic derived from Streptomyces spectabilis. It is active against gram-positive and gram-negative bacteria. Spectinomycin binds to the 30S subunit of bacterial ribosomes and suppresses protein synthesis.

  • Loss on drying: <20%

Spectinomycin has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused by Pasteurella multocida and Mannheimia haemolytica, and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media

Spectinomycin inhibits protein synthesis (elongation) by interfering with peptidyl tRNA translocation. Its mode of resistance is by mutation in rpsE (the gene for ribosomal protein S5) and thus prevents binding of spectinomycin.

Spectinomycin also has use in amplification of low copy number plasmid carrying replicons.

White powder

Soluble in water (50 mg/mL), methanol, propyleneglycol; very soluble benzene, chloroform, ethanol and acetone


Formula: C₁₄H₂₄N₂O₇·2HCl·5H₂O
MW: 495.35 g/mol
Melting Pt: 205…207 °C
Storage Temperature: Refrigerator
 MDL Number: MFCD00150886
CAS Number: 22189-32-8
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