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β-Dihydronicotinamide adenine dinucleotide disodium salt (NADH-Na₂, reduced form) ≥98%

Supplier: E. Becker & Co. GmbH

0216005050 0216005080 0216005083 0216005090 0216005091
IC16005050EA 53.69 USD InStock
IC16005050 IC16005080 IC16005083 IC16005090 IC16005091
β-Dihydronicotinamide adenine dinucleotide disodium salt (NADH-Na₂, reduced form) ≥98%
β-Dihydronicotinamide adenine dinucleotide disodium salt (NADH-Na2, reduced form)
Soluble in water or aqueous buffers (50 mg/mL); soluble in 0.01 N Sodium hydroxide (100 mg/mL - clear to slightly hazy, yellowish solution).

A high purity preparation of NADH suitable for most applications.

Meets or exceeds NRC specifications

β-NADH a pyridine nucleotide and biologically active form of nicotinic acid, is a coenzyme necessary for the catalytic reaction of certain enzymes.

β-Nicotinamide adenine dinucleotide and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases). As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

NADH is a coenzyme that functions as a regenerating electron donor in catabolic processes including glycolysis, beta-oxidation and the citric acid cycle (Krebs cycle, TCA cycle). It participates in cell signaling events as well, for example as a substrate for the poly (ADP-ribose) polymerases (PARPs) during the DNA damage response. The NAD+/NADH dependent sirtuins play key roles in stress responses during events involving energy metabolism, with implications in cancer biology, diabetes and neurodegenerative disease.

Precaución: pH 7,5 - 9,5 (10% aq soln)
Store at −0 °C. Store desiccated. Protect from light. Store under nitrogen.


Formula: C₂₁H₂₇N₇Na₂O₁₄P₂
MW: 709.41 g/mol
 MDL Number: MFCD00036200
CAS Number: 606-68-8
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Specification Test Results
Synonyms β-NADH, 2Na; Reduced DPN; Cozymase, reduced form; Dihydrophosphopyridine nucleotide; Dihydronicotinamide adenine dinucleotide; Diphosphopyridine nucleotide, reduced form; β-DPNH; DPNH; NADH
Form White Powder
Storage Store at -0 °C. Store desiccated. Protect from light. Store under nitrogen.
pH 7.5 - 9.5 (10% aq soln)

 

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