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Toluene-α-sulphonyl fluoride, white to off white needle crystals

Supplier: E. Becker & Co. GmbH
Danger

02195381.2 0219538101 0219538105 0219538125 0219538180
IC195381.2EA 62.3 USD InStock
IC195381.2 IC19538101 IC19538105 IC19538125 IC19538180
Toluene-α-sulphonyl fluoride, white to off white needle crystals
Toluene-α-sulphonyl fluoride
Phenylmethylsulfonyl fluoride is an irreversible inhibitor of serine proteases - inhibits trypsin, chymotrypsin and protease. Inhibits mammalian acetyl cholinesterase, but not those from fish sources.

  • Presentation: White to off white needle crystals
  • Causes sulfonylation of the active-site serine residue
  • A less toxic substitute for the extremely toxic diisopropylfluorophosphate

Phenylmethylsulfonyl fluoride inhibits serine proteases such as trypsin and chymotrypsin. Also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase.
Administration of PMSF produces analgesia unrelated to its anticholinesterase effect, and prolongs the analagesic effect of centrally administered β-endorphin.

Soluble in methanol and ethanol

Phenylmethylsulfonyl fluoride is an irreversible inhibitor of serine proteases - inhibits trypsin, chymotrypsin and protease. Causes sulfonylation of the active-site serine residue. A less toxic substitute for the extremely toxic diisopropylfluorophosphate. Inhibits mammalian acetyl cholinesterase, but not those from fish sources. Recommended concentration is 15 to 175 ug/mL.


Formula: C₇H₇FO₂S
MW: 174.2 g/mol
Melting Pt: 89…99 °C
Storage Temperature: Refrigerator
 MDL Number: MFCD00007424
CAS Number: 329-98-6
UN: 2928
ADR: 6.1 II
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