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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Ristocetin A ≥90%, powder

Supplier: E. Becker & Co. GmbH

0219548905 0219548925
IC19548905EA 94.44 USD InStock
IC19548905 IC19548925
Ristocetin A ≥90%, powder
Ristocetin A
Ristocetin A is an antibiotic that belongs to the class III glycopeptides. The compound has activity against gram-positive and gram-negative bacteria, and can be used in chromatography. Ristocetin A is structurally related to the glycopeptide antibiotics Teicoplanin and vancomycin.

Ristocetin A has platelet aggregating activity and has been used in platelet aggregation studies. Studies have demonstrated that Ristocentin A dimerizes and creates two binding sites for cell wall peptides.

Ristocetin activates platelets. Ristocetin-induced platelet agglutination (RIPA) is decreased in patients undergoing chronic hemodialysis. Together with increased plasma glycocalicin levels (a product of enzymatic cleavage of GPIb), RIPA may contribute to diminished platelet adhesion to vascular subendothelium and increased bleeding associated with uremia. Addition of ristocetin and vWf caused specific agglutination of rGPIbα-liposomes suporting the potential use of rGPIbα-liposomes to enhance platelet function in vivo and support hemostasis in thrombocytopenic individuals.

Soluble in 1 N HCl (50 mg/mL - clear and colorless to pale yellow); soluble in water (clear 5 mg+ 0.25 mL, amber solution).

Ristocetin A is an antibiotic that belongs to the class III glycopeptides. The compound has activity against gram-positive and gram-negative bacteria, and can be used in chromatography. Ristocetin A is structurally related to the glycopeptide antibiotics Teicoplanin and vancomycin.


Formula: C₉₅H₁₁₀N₈O₄₄
 CAS Number: 1404-55-3
https://qa.digitalassets.avantorsciences.com/adaptivemedia/rendition?id=8958067391cf874a8b0c33b569659a8f53734467&vid=8958067391cf874a8b0c33b569659a8f53734467&prid=web&clid=SAPDAM
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Specification Test Results
Identity Test Passes
Potency (µg/mg) Report Result
Purity ≥90% Ristocetin A
Ristocetin B Sulfate Report Result

 

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