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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Vancomycin hydrochloride (from Streptomyces orientalis), powder

Supplier: E. Becker & Co. GmbH

02195540.1 02195540.2 0219554001
IC195540.1EA 67.69 USD InStock
IC195540.1 IC195540.2 IC19554001
Vancomycin hydrochloride (from Streptomyces orientalis), powder
Vancomycin hydrochloride
Vancomycin inhibits bacterial mucopeptide biosynthesis

  • Presentation: White Powder
  • Potency: 1000 µg/mg
  • Soluble in water (greater than 100 mg/mL). Moderately soluble in dilute methanol. Insoluble in acetone, alcohols, and ether.
  • pH: 2.5 - 4.5 (5% aq solution)

Vancomycin is indicated for the treatment of serious, life-threatening infections by Gram-positive bacteria that are unresponsive to other less-toxic antibiotics. In particular, vancomycin should not be used to treat methicillin-sensitive Staphylococcus aureus because it is inferior to penicillins such as nafcillin.

Vancomycin, from Streptomyces orientalis, is used for the treatment of serious or severe infections caused by susceptible strains of methicillin-resistant (β-lactam-resistant) staphylococci. It is used to block bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis. It is widely studied in cancer patients.

Glycopeptide antibiotic Mode of action: Used to block bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis by inhibiting incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides.
Antimicrobial spectrum: Gram-positive bacteria.

Vancomycin is a glycopeptide antibiotic that blocks bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis. It inhibits incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. It is effective against Gram-positive bacteria. Vancomycin also alters bacterial-cell-membrane permeability and RNA synthesis.

Soluble in water (>100 mg/mL). Moderately soluble in dilute methanol. Insoluble in acetone, alcohols, and ether.

Precaución: Store under nitrogen


Formula: C₆₆H₇₅Cl₂N₉O₂₄·HCl
Storage Temperature: Refrigerator
 MDL Number: MFCD03613611
CAS Number: 1404-93-9
https://qa.digitalassets.avantorsciences.com/adaptivemedia/rendition?id=dc640c3e604d6a66b2d38c6b25a24a4e5f3645e8&vid=dc640c3e604d6a66b2d38c6b25a24a4e5f3645e8&prid=web&clid=SAPDAM https://qa.digitalassets.avantorsciences.com/adaptivemedia/rendition?id=8ed51be44a499d289d8482cf71f2adfea93dcfb1&vid=8ed51be44a499d289d8482cf71f2adfea93dcfb1&prid=web&clid=SAPDAM
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Specification Test Results
Identity Test Passes
Potency ~1000 μg/mg
FTIR Conforms to Standard
pH (5% aq soln) 2.5-4.5

 

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