AF-200-06-5UG
AF-200-06-20UG
AF-200-06-50UG
AF-200-06-100UG
AF-200-06-250UG
AF-200-06-500UG
AF-200-06-1MG
10778-280EA
180.86
USD
InStock
10778-280
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Human Recombinant IL6 (from E. coli)
Proteins and Peptides
IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6Rα and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant Human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.Manufactured using all Animal-Free reagents.
PVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM
Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Información para pedidos: For research use only. Not for use in diagnostic or therapeutic procedures.