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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Tris(hydroxymethyl)aminomethane (TRIS, Trometamol) 99.0-101.0% JPC, USP, Ph. Eur., BP suitable for use as excipient endotoxin tested

Supplier: VWR Aurora Production
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VWRB497-12KG VWRB497-500G VWRB497-50KG
VWRB497-12KGEA 3295.67 USD InStock
VWRB497-12KG VWRB497-500G VWRB497-50KG
Tris(hydroxymethyl)aminomethane (TRIS, Trometamol) 99.0-101.0% JPC, USP, Ph. Eur., BP suitable for use as excipient endotoxin tested
Tris(hydroxymethyl)aminomethane (TRIS, Trometamol)
Suitable for bioprocessing. BSE/TSE free. Endotoxin tested. Custom packaging and testing available. Change management and notification available. Samples available.


Formula: NH₂C(CH₂OH)₃
MW: 121.14 g/mol
Boiling Pt: 357
Melting Pt: 169…172 °C
Density: 1.328 g/cm³ (20 °C)
 MDL Number: MFCD00004679
CAS Number: 77-86-1
Merck Index: 13,09842
https://qa.digitalassets.avantorsciences.com/adaptivemedia/rendition?id=11a03d1ab6b2c11b9a2c83f0a73fc4264cec0110&vid=b84ca1743f9dfe50eb47c249460ab41a6772ceb2&prid=web&clid=SAPDAM
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Specification Test Results
Assay (USP) 99.0 – 101.0%
Endotoxins (USP) ≤ 2.5EU/g
Heavy Metals <231> (USP) ≤10 ppm
Identification A (USP) PASS
Identification B (USP) PASS
Identification C (USP) PASS
Loss on Drying <731> (USP) ≤ 1.0%
Melting range or temperature (USP) 168⁰ - 172⁰C
pH <791> (USP) 10.0 – 11.5
Residue on Ignition (USP) ≤ 0.1%
Appearance of Solution (EP & BP) PASS
Assay (EP & BP) 99.0 – 100.5%
Chlorides (2.4.4) (EP & BP) ≤100 ppm
Heavy Metals (2.4.8) (EP & BP) ≤10 ppm
Identification B (EP & BP) PASS
Identification C (EP & BP) PASS
Iron (2.4.9) (EP & BP) ≤10 ppm
Loss on Drying (2.2.32) (EP & BP) ≤0.5%
pH (2.2.3) (EP & BP) 10.0 – 11.5
Related Substances (2.2.27) (EP & BP) ≤1.0%
Sulfated Ash (2.4.14) (EP & BP) ≤0.1%
Arsenic (JPC) ≤1.6 ppm
Assay (JPC) ≥99.0%
Clarity and Color of Solution (JPC) PASS
Heavy Metals (JPC) ≤8 ppm
Identification (1)(JPC) PASS
Identification (2)(JPC) PASS
Loss on Drying (JPC) ≤0.5%
Melting Point (JPC) 168⁰C - 172⁰C
pH (1.0g/100mL water)@25⁰C (JPC) 10.3 – 10.7
Residue on Ignition (JPC) ≤0.10%

 

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