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N-Methyl-N-(trimethylsilyl)trifluoroacetamide for GC derivatisation

Supplier: Kubota Brabender Technologie GmbH
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35600 35601
10058-068EA 214.58 USD InStock
10058-068 75835-394
N-Methyl-N-(trimethylsilyl)trifluoroacetamide for GC derivatisation
N-Methyl-N-(trimethylsilyl)trifluoroacetamide
Silylation derivatization reagent.

  • Replace active hydrogen, reducing polarity and making the compounds more volatile.
  • Increase stability of derivatives.

Silylation is the most widely used derivatization procedure for sample analysis by GC. In silylation, an active hydrogen is replaced by an alkylsilyl group such as trimethylsilyl (TMS) or tert-butyldimethylsilyl (tert-BDMS). Silyl derivatives are more volatile, less polar, and more thermally stable. As a result, GC separation is improved and detection is enhanced. Both TMS and tert-BDMS reagents are suitable for a wide variety of compounds and can be used for many GC applications. (Note that silylation reagents are generally moisture-sensitive and must be sealed to prevent deactivation.)


Formula: C₆H₁₂F₃NOSi
MW: 199.25 g/mol
Boiling Pt: 130
 MDL Number: MFCD00000411
CAS Number: 24589-78-4
EINECS: 246-331-6
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